Long-Acting Thyroid Stimulator

Known as: Thyroid Stimulator, Long-Acting, Long Acting Thyroid Stimulator, Thyroid Stimulator, Long Acting 
An immunoglobulin G, often found in the blood of hyperthyroid individuals. It stimulates the thyroid for a longer duration than does thyrotoxin and… (More)
National Institutes of Health

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9 relations
HyperthyroidismIn BloodThyroid Hormone ReceptorThyroid stimulating immunoglobulins
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Broader (1)

Immunologic Factors

Papers overview

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Highly Cited
2010
Highly Cited
2010
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP).
The Yes-associated protein (YAP) transcription coactivator is a key regulator of organ size and a candidate human oncogene. YAP… (More)
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Highly Cited
2009
Highly Cited
2009
The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass.
Outside cells of the preimplantation mouse embryo form the trophectoderm (TE), a process requiring the transcription factor Tead4… (More)
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Highly Cited
2008
Highly Cited
2008
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway.
TAZ is a WW domain containing a transcription coactivator that modulates mesenchymal differentiation and development of multiple… (More)
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Highly Cited
2008
Highly Cited
2008
Tumor suppressor LATS1 is a negative regulator of oncogene YAP.
LATS (large tumor suppressor) or warts is a Ser/Thr kinase that belongs to the Ndr/LATS subfamily of AGC (protein kinase A/PKG… (More)
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Highly Cited
2008
Highly Cited
2008
Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway.
The Hippo pathway defines a novel signaling cascade regulating cell proliferation and survival in Drosophila, which involves the… (More)
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Highly Cited
2005
Highly Cited
2005
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1
Originally identified in Drosophila melanogaster, the Warts(Wts)/Lats protein kinase has been proposed to function with two other… (More)
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Highly Cited
1999
Highly Cited
1999
Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction
The lats gene has been identified as a tumour suppressor in Drosophila melanogaster using mosaic screens. Mosaic flies carrying… (More)
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Highly Cited
1995
Highly Cited
1995
Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase.
We have identified recessive overproliferation mutations by screening and examining clones of mutant cells in genetic mosaics of… (More)
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Review
1970
Review
1970
[Long-acting thyroid stimulator (LATS)].
1. INTENDED USE The MRC Research Standard B for Long-acting Thyroid Stimulator (LATS-B) is a serum sample from a single patient… (More)
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1966
1966
Inhibition of long-acting thyroid stimulator by thyroid particulate fractions.
The long-acting thyroid stimulator (LATS), found uniquely in the serum of patients with Graves' disease, is closely associated… (More)
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