Logiparin
National Institutes of Health
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The antithrombotic drug heparin is administered parenterally and believed not effective orally. Oral heparin would be most…
Summary Previous studies in rats show that unfractionated heparin and the low molecular weight heparin logiparin have a dose…
Previous studies in rats demonstrated that orally administered, unfractionated bovine lung heparin is absorbed and has a dose…
Summary Low molecular weight (LMW) heparins have prolonged circulating half-lives relative to unfractionated heparin, but the…
Protamine reversal of unfractionated and low-molecular-weight heparin (LMWH) causes hypotension, bradycardia, pulmonary artery…
Increased calcium uptake in vascular tissue, leading to elevated cytosolic free calcium has been implicated in the…
In a randomized double-blind placebo-controlled study, plasma levels of prothrombin fragment 1 and 2 and total fibrin/fibrinogen…
In order to study the plasma levels of factor XaI and IIaI activity an enzymatically depolymerized low molecular weight heparin…