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Liver Kidney Microsomal Type 1 Antibody Measurement

Known as: LKM-1, LKM1AB, Liver Kidney Microsomal Type 1 Antibody 
The determination of the amount of liver kidney microsomal type 1 antibody present in a sample.
National Institutes of Health

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CDISC SDTM Laboratory Test Terminology by CodeCDISC SDTM Laboratory Test Terminology by NameClinical Data Interchange Standards Consortium Terminology

Papers overview

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2005
2005
The Prevalence, Clinical Features and Response to Antiviral Therapy of Patients with Chronic Hepatitis C who are Seropositive for Liver–Kidney Microsome Type 1 Antibodies
Background Antibodies to liver–kidney microsome type 1 (anti-LKM-1), which are a marker of autoimmune hepatitis, are found in a… 
2004
2004
Prevalence of Non-Organ-Specific Autoantibodies in Patients Suffering from Duodenal Ulcer With and Without Helicobacter pylori Infection
Autoimmunity, a feature of chronic infection by Helicobacter pylori, is first directed against gastric cells but is also… 
2002
2002
The prevalence of autoimmune hepatitis in Hashimoto's thyroiditis in a Turkish population.
PURPOSE Hashimoto's thyroiditis (HT) is an autoimmune thyroid disorder. Although its etiopathogenesis is obscure, there are many… 
2001
2001
Differences in anti-LKM-1 autoantibody immunoreactivity to CYP2D6 antigenic sites between hepatitis C virus-negative and -positive patients.
Anti-liver kidney microsome type 1 autoantibodies (anti-LKM-1) are known to be present in sera of autoimmune hepatitis type II… 
2001
2001
T cell receptor Vbeta chain restriction and preferred CDR3 motifs of liver-kidney microsomal antigen (LKM-1)-reactive T cells from autoimmune hepatitis patients.
AIMS/BACKGROUND The liver-kidney-microsomal antigen (LKM-1) has been recognized as a major CD4+ T cell antigen in autoimmune… 
1998
1998
Interferon therapy in LKM-1 positive patients with chronic hepatitis C: follow-up by a quantitative radioligand assay for CYP2D6 antibody detection.
Highly Cited
1997
Highly Cited
1997
Establishment of a novel radioligand assay using eukaryotically expressed cytochrome P4502D6 for the measurement of liver kidney microsomal type 1 antibody in patients with autoimmune hepatitis and…
Review
1993
Review
1993
Viruses and autoimmune liver disease.
Autoimmune hepatitis is characterized by hypergammaglobulinemia, female predominance, autoantibodies and a good response to… 
1993
1993
Anti‐LKM‐1 antibodies determined by use of recombinant P450 2D6 in ELISA and Western blot and their association with anti‐HCV and HCV‐RNA
Several subtypes of anti‐liver‐kidney microsome antibodies (LKM) are known, LKM‐1 antibodies associated with autoimmune chronic… 
1993
1993
Lack of surface expression for the B-cell autoepitope of cytochrome P450 IID6 evidenced by flow cytometry.
The major target antigen of LKM-1 autoantibodies in chronic active hepatitis is cytochrome P450 IID6. The role of LKM-1… 
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