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Little's Disease

Known as: spastic infantile paralysis, Diplegia, Spastic, Little Disease 
A type of cerebral palsy characterized by spasticity and hypertonia of the lower extremities bilaterally, particularly the legs, hips, and pelvis… 
National Institutes of Health

Related topics

Related topics

24 relations
Athetoid cerebral palsyBrooks-Wisniewski-Brown SyndromeCentral Nervous SystemCerebral Palsy

Broader (3)

Diplegic Infantile Cerebral PalsyParalytic syndromenervous system disorder

Narrower (1)

Spastic diplegia infantile type

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Single-event multilevel surgery in children with spastic diplegia: a pilot randomized controlled trial.
BACKGROUND Single-event multilevel surgery is considered the standard of care to improve gait and functioning of children with… 
Review
2009
Review
2009
Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity.
Aicardi-Goutières syndrome (AGS) is a genetically determined encephalopathy demonstrating phenotypic overlap both with the… 
Highly Cited
2006
Highly Cited
2006
Correction of severe crouch gait in patients with spastic diplegia with use of multilevel orthopaedic surgery.
BACKGROUND Severe crouch gait in patients with spastic diplegia causes excessive loading of the patellofemoral joint and may… 
Highly Cited
2001
Highly Cited
2001
Architecture of the medial gastrocnemius in children with spastic diplegia
Ultrasound images were obtained of the medial gastrocnemius at different ankle joint positions with the knee extended. Fascicle… 
Highly Cited
1998
Highly Cited
1998
Lower‐Extremity strength profiles in spastic cerebral palsy
Although weakness has been identified in cerebral palsy (CP) in isolated muscle groups, the magnitude of weakness in multiple… 
Highly Cited
1997
Highly Cited
1997
The evolution of gait in childhood and adolescent cerebral palsy.
A longitudinal study over a mean of 32 months was conducted on 18 subjects with spastic diplegia, ranging in age from 4 to 14… 
Highly Cited
1995
Highly Cited
1995
Effects Of Quadriceps Femoris Muscle Strengthening On Crouch Gait In Children With Spastic Diplegia
BACKGROUND AND PURPOSE Despite evidence of weakness in children with cerebral palsy, the use of strength training in this… 
Highly Cited
1993
Highly Cited
1993
Simultaneous multiple operations for spastic diplegia. Outcome and functional assessment of walking in 18 patients.
We assessed the outcome after simultaneous multiple operations performed on 18 children with spastic diplegia, with emphasis on… 
Highly Cited
1991
Highly Cited
1991
Neurodevelopmental, health, and growth status at age 6 years of children with birth weights less than 1001 grams.
Highly Cited
1988
Highly Cited
1988
The effects of physical therapy on cerebral palsy. A controlled trial in infants with spastic diplegia.
Legislatively mandated programs for early intervention on behalf of handicapped infants often stipulate the inclusion of physical… 
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