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Liposomal MnSOD Plasmid

Known as: MnSOD Plasmid Liposomes, MnSOD-PL 
A plasmid DNA encoding human manganese superoxide dismutase (MnSOD) and liposomally encapsulated with potential chemoprotective activity. When… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Molecular cloning and oxidative-stress responses of a novel manganese superoxide dismutase (MnSOD) gene in the dinoflagellate Prorocentrum minimum
Dinoflagellate algae are microeukaryotes that have distinct genomes and gene regulation systems, making them an interesting model… 
2013
2013
Association Between Environmental Tobacco Smoke Exposure and Lung Cancer Susceptibility: Modification by Antioxidant Enzyme Genetic Polymorphisms
Environmental tobacco smoke (ETS) is the primary etiologic factor responsible for lung cancer. However, only 10–15 % of smokers… 
2013
2013
Manganese superoxide dismutase gene therapy protects against irradiation- induced intestinal injury.
Radiation-induced intestinal injury is a common complication in radiotherapy for solid organ malignancies in abdomen or pelvis… 
2010
2010
Lack of association between MnSOD Val16Ala polymorphism and breast cancer risk: a meta-analysis involving 58,448 subjects
Published data on the association between MnSOD Val16Ala polymorphism and breast cancer risk are inconclusive. To derive a more… 
2010
2010
Possible risk modifications in the association between MnSOD Ala-9Val polymorphism and breast cancer risk: subgroup analysis and evidence-based sample size calculation for a future trial
Manganese superoxide dismutase (MnSOD) has been identified as an important scavenger of reactive oxygen species (ROS), which can… 
2009
2009
Enhancing the antitumor activity of adriamycin and ionizing radiation.
Overexpression of manganese superoxide dismutase (MnSOD), when combined with certain chemicals that inhibit peroxide removal… 
2008
2008
Radioprotection In Vitro and In Vivo by Mini Circle Plasmid Containing the Human Manganese Superoxide Dismutase (MnSOD) Transgene
Manganese superoxide dismutase-plasmid liposomes (MnSOD-PL) confer organ specific in vivo ionizing irradiation protection. To… 
2006
2006
Effect of EGFR antagonists gefitinib (Iressa) and C225 (Cetuximab) on MnSOD-plasmid liposome transgene radiosensitization of a murine squamous cell carcinoma cell line.
Radiation therapy of tumors of the head and neck region is compromised by dose limiting toxicity of normal tissues including the… 
2005
2005
Protection of esophageal multi-lineage progenitors of squamous epithelium (stem cells) from ionizing irradiation by manganese superoxide dismutase-plasmid/liposome (MnSOD-PL) gene therapy.
BACKGROUND Intraesophageal manganese superoxide dismutase plasmid liposome (MnSOD-PL) gene therapy protects against irradiation… 
1998
1998
Chromosome‐6‐mediated suppression of metastatic ability increases basal expression of UV‐inducible superoxide dismutase and induction of p53
Since response to radiation and markers capable of distinguishing metastatic from non‐metastatic cells are important, we now use… 
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