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Linkage Disequilibrium Mapping

Linkage disequilibrium (LD) mapping is a procedure for determining the non-random association of alleles at two or more loci on a chromosome. It is… Expand
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
This paper describes two joint linkage–linkage disequilibrium (LD) mapping approaches: parallel mapping (independent linkage and… Expand
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Highly Cited
2004
Highly Cited
2004
Associations between markers and complex quantitative traits were investigated in a collection of 146 modern two-row spring… Expand
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Highly Cited
2004
Highly Cited
2004
The selfing plant Arabidopsis thaliana has been proposed to be well suited for linkage disequilibrium (LD) mapping as a means of… Expand
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Highly Cited
2004
Highly Cited
2004
Previously, we have reported linkage of markers from chromosome 1q22 to schizophrenia, a finding supported by several independent… Expand
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Highly Cited
2002
Highly Cited
2002
A novel and robust method for the fine-scale mapping of genes affecting complex traits, which combines linkage and linkage… Expand
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Highly Cited
2000
Highly Cited
2000
We introduce a new method for linkage disequilibrium mapping: haplotype pattern mining (HPM). The method, inspired by data mining… Expand
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Highly Cited
1999
Highly Cited
1999
Recently, attention has focused on the use of whole-genome linkage disequilibrium (LD) studies to map common disease genes. Such… Expand
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Review
1998
Review
1998
In the past year, data about the level and nature of linkage disequilibrium between alleles of tightly linked SNPs have started… Expand
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Highly Cited
1994
Highly Cited
1994
Diastrophic dysplasia (DTD) is a well-characterized autosomal recessive osteochondrodysplasia with clinical features including… Expand
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Highly Cited
1992
Highly Cited
1992
Linkage disequilibrium mapping in isolated populations provides a powerful tool for fine structure localization of disease genes… Expand
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