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Linkage Disequilibrium Mapping

Linkage disequilibrium (LD) mapping is a procedure for determining the non-random association of alleles at two or more loci on a chromosome. It is… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Association Mapping With Single-Feature Polymorphisms
We develop methods for exploiting “single-feature polymorphism” data, generated by hybridizing genomic DNA to oligonucleotide… 
Review
2005
Review
2005
Genetics in coeliac disease.
2005
2005
Discovery of genetic difference between asthmatic children with high IgE level and normal IgE level by whole genome linkage disequilibrium mapping using 763 autosomal STR markers
AbstractThe genome-wide linkage disequilibrium screen for loci associated with genetic difference between allergic and… 
2005
2005
Fine mapping of a QTL for intramuscular fat on porcine chromosome 6 using combined linkage and linkage disequilibrium mapping.
In this study data from a commercial Norwegian slaughter pig cross was analysed to confirm a previous reported quantitative trait… 
2005
2005
Haplotype-based linkage disequilibrium mapping via direct data mining
MOTIVATION With the availability of large-scale, high-density single-nucleotide polymorphism markers and information on haplotype… 
2002
2002
Linkage disequilibrium mapping identifies a 390 kb region associated with CYP2D6 poor drug metabolising activity
The cytochrome p450 enzyme, CYP2D6, metabolises approximately 20% of marketed drugs. CYP2D6 multiple variants are associated with… 
Highly Cited
1999
Highly Cited
1999
EVIDENCE FOR AN EXTREME BOTTLENECK IN A RARE MEXICAN PINYON: GENETIC DIVERSITY, DISEQUILIBRIUM, AND THE MATING SYSTEM IN PINUS MAXIMARTINEZII
Maxipiñon (Pinus maximartinezii Rzedowski), which is confined to a single population of approximately 2000 to 2500 mature trees… 
1999
1999
Multipoint linkage disequilibrium mapping with particular reference to the African‐American population
A new approach to scanning the genome is presented to detect linkage disequilibrium caused specifically by population admixture… 
Highly Cited
1995
Highly Cited
1995
Analysis of the CD3 gene region and type 1 diabetes: application of fluorescence-based technology to linkage disequilibrium mapping.
The CD3 gene region on chromosome 11q23 has been implicated in susceptibility to type 1 (insulin-dependent) diabetes mellitus… 
1995
1995
Linkage disequilibrium mapping of the cornea plana congenita gene CNA2.
We recently assigned a gene for autosomal recessive cornea plana congenita (CNA2; MIM No. 217300) by linkage analysis to the… 
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