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Licofelone

Known as: 6-(4-Chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizine-5-acetic Acid, (2,2-dimethyl-6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl)acetic acid, 2,3-Dihydro-6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-1H-pyrrolizine-5-acetic Acid 
National Institutes of Health

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2 relations

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ML-3000

Broader (1)

Pyrroles

Papers overview

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2018
2018
DUAL LOX/COX INHIBITION: A NOVEL STRATEGY TO PREVENT NEUROVASCULAR LEAKAGE IN EPILEPSY
OF THESIS DUAL LOX/COX INHIBITION: A NOVEL STRATEGY TO PREVENT NEUROVASCULAR LEAKAGE IN EPILEPSY Epilepsy affects 3.4 million… 
2017
2017
Effects of licofelone, a novel 5-LOX inhibitor, in comparison to celecoxib on gastric mucosa of dogs
Despite the extensive application of nonsteroidal anti-inflammatory drugs (NSAIDs), the use of these drugs is limited due to… 
2014
2014
Lipid Accumulation After Rotator Cuff Repair Inhibition of 5-LOX , COX-1 , and COX-2 Increases Tendon Healing and Reduces Muscle Fibrosis and
http://ajs.sagepub.com/content/early/2014/09/22/0363546514549943 The online version of this article can be found at: DOI: 10.1177… 
Review
2014
Review
2014
Chapter 2 The Role of Inflammation in Colon Cancer
Abstract Colorectal cancer (CRC) is the one of the leading causes of cancer-related deaths in the world. CRC is responsible for… 
2012
2012
Polypharmacology in drug discovery
List of contributors. Preface. Introduction: the case for polypharmacology Andrew L. Hopkins Part A: Polypharmacology a safety… 
2012
2012
Abstract 1005: Targeting COX-LOX and EGFR pathways simultaneously by licofelone and gefitinib lead to complete blockade of progression of PanINs to pancreatic ductal adenocarcinoma
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL Pancreatic ductal adenocarcinoma (PDAC), a… 
Review
2011
Review
2011
Licofelone: A Novel Non-Steriodal Anti-Inflammatory Drug (NSAID) in Arthritis
Arthritis refers to different medical conditions associated with disorder of the primary structures that determine joint… 
2010
2010
Abstract 2869: Chemopreventive efficacy and mechanism of licofelone in mouse lung tumor model
Our previous study comparing inhalation and aspiration methods of administration of an agent to lung airway epithelia indicated… 
2008
2008
Quantitative MRI provides insights into the efficacy of licofelone for knee OA
2004
2004
Formulation pharmaceutique de licofelone
L'invention concerne une formulation pharmaceutique solide contenant du licofelone ou un sel physiologiquement acceptable de… 
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