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Licofelone

Known as: 6-(4-Chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-1H-pyrrolizine-5-acetic Acid, (2,2-dimethyl-6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl)acetic acid, 2,3-Dihydro-6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-1H-pyrrolizine-5-acetic Acid 
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Colorectal cancer (CRC) is the one of the leading causes of cancer-related deaths in the world. CRC is responsible for more than… Expand
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Review
2011
Review
2011
Unresolved inflammation, due to insufficient production of proresolving anti-inflammatory lipid mediators, can lead to an… Expand
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Highly Cited
2009
Highly Cited
2009
Objective: In a multicentre study to explore the effects of licofelone as a disease-modifying osteoarthritis drug in comparison… Expand
Highly Cited
2008
Highly Cited
2008
The anti-inflammatory drug licofelone [=ML3000; 2-[6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl… Expand
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Highly Cited
2008
Highly Cited
2008
Nowadays, no data are available concerning the potential use of dual cyclooxygenase (COX)/5-lipoxygenase (LOX) inhibitors as… Expand
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Highly Cited
2007
Highly Cited
2007
Licofelone, a dual anti-inflammatory drug that inhibits 5-lipoxygenase (LOX) and cyclooxygenase (COX) enzymes, may have a better… Expand
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2007
2007
To evaluate the effect of licofelone, an arachidonic acid substrate with combined inhibitory activity against 5-lipoxygenase and… Expand
Highly Cited
2004
Highly Cited
2004
OBJECTIVE To evaluate the morphological changes that take place in the subchondral bone and calcified cartilage zone in the… Expand
Highly Cited
2004
Highly Cited
2004
OBJECTIVES:Concerns exist over the safety of conventional nonsteroidal antiinflammatory drugs (NSAIDs) and selective… Expand
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Review
2003
Review
2003
Dual COX/5-LOX (cyclooxygenase/5-lipoxygenase) inhibitors constitute a valuable alternative to classical non-steroidal anti… Expand
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