Leydig cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1970-2017
0246819702017

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2011
2011
Leydig cells are the testosterone-producing cells in the adult male. Adult Leydig cells (ALCs) develop from stem Leydig cells… (More)
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2008
2008
Chicken Ovalbumin Upstream Promoter-Transcription Factor II (COUP-TFII; also known as NR2F2), is an orphan nuclear receptor of… (More)
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Highly Cited
2003
Highly Cited
2003
During testis development, the rapid morphological changes initiated by Sry require the coordinate integration of many signaling… (More)
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Highly Cited
2003
Highly Cited
2003
The signalling molecule WNT4 has been associated with sex reversal phenotypes in mammals. Here we show that the role of WNT4 in… (More)
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Highly Cited
2002
Highly Cited
2002
Establishment of the steroid-producing Leydig cell lineage is an event downstream of Sry that is critical for masculinization of… (More)
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Highly Cited
2002
Highly Cited
2002
Developmental changes in the expression of 18 Leydig cell-specific mRNA species were measured by real-time polymerase chain… (More)
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Highly Cited
2000
Highly Cited
2000
The Kit receptor tyrosine kinase functions in hemato- poiesis, melanogenesis and gametogenesis. Kit receptor-mediated cellular… (More)
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1998
1998
Strong overexpression of anti-Müllerian hormone (AMH) in transgenic mice leads to incomplete fetal virilization and decreased… (More)
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1996
1996
The human LH receptor (hLHR) is a member of the G protein-coupled receptors characterized by the presence of seven-transmembrane… (More)
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1985
1985
The process of early testosterone (T) secretion and Leydig cell differentiation in humans was studied to explore the… (More)
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