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Leukemia, Large Granular Lymphocytic

Known as: Lymphoproliferative Disease of Large Granular Lymphocytes, Aggressive NK Cell Leukemia, LGL (large granular lymphocyte) leukemia 
A spectrum of disorders characterized by clonal expansions of the peripheral blood LYMPHOCYTE populations known as large granular lymphocytes which… 
National Institutes of Health

Related topics

Related topics

10 relations
Aggressive natural killer-cell leukemiaIn BloodLymphocytosisMicrobiological

Narrower (2)

Leukemia, Natural Killer Cell Large Granular LymphocyticT-Cell Large Granular Lymphocyte Leukemia

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
LGL leukemia: from pathogenesis to treatment.
Large granular lymphocyte (LGL) leukemia has been recognized by the World Health Organization classifications amongst mature T… 
Highly Cited
2014
Highly Cited
2014
Autoimmune diseases associated with non-Hodgkin lymphoma: a nationwide cohort study.
BACKGROUND The cumulative risk of non-Hodgkin lymphoma (NHL) in Sweden by age 80 years has increased to 1.1 in women and 1.6% in… 
Highly Cited
2011
Highly Cited
2011
How I treat LGL leukemia.
Large granular lymphocyte (LGL) leukemia is characterized by a clonal expansion of either CD3(+) cytotoxic T or CD3(-) NK cells… 
Highly Cited
2008
Highly Cited
2008
Network model of survival signaling in large granular lymphocyte leukemia
T cell large granular lymphocyte (T-LGL) leukemia features a clonal expansion of antigen-primed, competent, cytotoxic T… 
Review
1997
Review
1997
Nonnasal lymphoma expressing the natural killer cell marker CD56: a clinicopathologic study of 49 cases of an uncommon aggressive neoplasm.
Expression of the natural killer (NK) cell antigen CD56 is uncommon among lymphomas, and those that do are almost exclusively of… 
Highly Cited
1997
Highly Cited
1997
The lymphoproliferative disease of granular lymphocytes: updated criteria for diagnosis.
The lymphoproliferative disease of granular lymphocytes (LDGL), also referred to as LGL leukemia, is a heterogeneous disorder… 
Highly Cited
1994
Highly Cited
1994
Clinical spectrum of clonal proliferations of T-large granular lymphocytes: a T-cell clonopathy of undetermined significance?
We identified 68 patients with clonal T-large granular lymphocyte (T-LGL) proliferations who were seen at the Mayo Clinic between… 
Review
1993
Review
1993
Clonal diseases of large granular lymphocytes.
Three distinct clinical syndromes occur in patients with increased numbers of circulating LGL. Patients with T-LGL leukemia have… 
Highly Cited
1992
Highly Cited
1992
A natural killer cell granule protein that induces DNA fragmentation and apoptosis
We report the purification from a rat natural killer (RNK) large granular lymphocyte leukemia of a 32-kD granule protein that… 
Review
1989
Review
1989
CD3-negative lymphoproliferative disease of granular lymphocytes containing Epstein-Barr viral DNA.
Lymphoproliferative disease of granular lymphocytes (LDGL) is a heterogeneous disorder and the pathogenesis is likely to be… 
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