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Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
Known as:
Leukemia, Myeloid, Chronic, Atypical
, Leukemia, Philadelphia-Negative Myeloid
, ACML
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A myelodysplastic/myeloproliferative disorder characterized by myelodysplasia associated with bone marrow and peripheral blood patterns similar to…
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National Institutes of Health
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Related topics
Related topics
28 relations
Anemia
Bone Marrow
Bone marrow stem cell
CCDC6 gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Myelodysplastic Syndromes, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology.
P. Greenberg
,
R. Stone
,
+29 authors
Courtney Smith
The Journal of the National Comprehensive Cancer…
2017
Corpus ID: 21398138
The myelodysplastic syndromes (MDS) comprise a heterogenous group of myeloid disorders with a highly variable disease course…
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Highly Cited
2010
Highly Cited
2010
Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13.
S. Highfill
,
P. Rodriguez
,
+10 authors
B. Blazar
Blood
2010
Corpus ID: 206892504
Myeloid-derived suppressor cells (MDSCs) are a well-defined population of cells that accumulate in the tissue of tumor-bearing…
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Highly Cited
2010
Highly Cited
2010
Stable long‐term risk of leukaemia in patients with severe congenital neutropenia maintained on G‐CSF therapy
P. Rosenberg
,
C. Zeidler
,
+10 authors
D. Dale
British Journal of Haematology
2010
Corpus ID: 13787023
In severe congenital neutropenia (SCN), long‐term therapy with granulocyte colony‐stimulating factor (G‐CSF) has reduced…
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Review
2010
Review
2010
Copy neutral loss of heterozygosity: a novel chromosomal lesion in myeloid malignancies.
C. O’Keefe
,
M. McDevitt
,
J. Maciejewski
Blood
2010
Corpus ID: 657587
Single nucleotide polymorphism arrays (SNP-A) have recently been widely applied as a powerful karyotyping tool in numerous…
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Highly Cited
2008
Highly Cited
2008
Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms.
F. Grand
,
Claire E Hidalgo-Curtis
,
+14 authors
N. Cross
Blood
2008
Corpus ID: 11198717
Recent evidence has demonstrated that acquired uniparental disomy (aUPD) is a novel mechanism by which pathogenetic mutations in…
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Highly Cited
2008
Highly Cited
2008
250K single nucleotide polymorphism array karyotyping identifies acquired uniparental disomy and homozygous mutations, including novel missense substitutions of c-Cbl, in myeloid malignancies.
A. Dunbar
,
L. Gondek
,
+7 authors
J. Maciejewski
Cancer Research
2008
Corpus ID: 10797886
Two types of acquired loss of heterozygosity are possible in cancer: deletions and copy-neutral uniparental disomy (UPD…
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Highly Cited
2005
Highly Cited
2005
The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia.
R. Levine
,
M. Loriaux
,
+18 authors
M. Deininger
Blood
2005
Corpus ID: 9573544
Activating mutations in tyrosine kinases have been identified in hematopoietic and nonhematopoietic malignancies. Recently, we…
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Highly Cited
2003
Highly Cited
2003
Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9.
P. Ayton
,
M. Cleary
Genes & Development
2003
Corpus ID: 41766831
Transcriptional deregulation through the production of dominant-acting chimeric transcription factors derived from chromosomal…
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Review
1999
Review
1999
Myelofibrosis with myeloid metaplasia: diagnostic definition and prognostic classification for clinical studies and treatment guidelines.
G. Barosi
Journal of Clinical Oncology
1999
Corpus ID: 25404320
PURPOSE Myelofibrosis with myeloid metaplasia (MMM) is a chronic myeloproliferative disorder characterized by bone marrow…
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Highly Cited
1997
Highly Cited
1997
PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors.
Edward W. Scott
,
R. Fisher
,
M. Olson
,
Eli Kehrli
,
M. Simon
,
Harinder Singh
Immunity
1997
Corpus ID: 38684580
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