Lecithin Acyltransferase Deficiency

Known as: Norum Disease, Deficiency, LCAT, LECITHIN:CHOLESTEROL ACYLTRANSFERASE DEFICIENCY 
An autosomal recessive disorder of lipoprotein metabolism caused by mutation of LECITHIN CHOLESTEROL ACYLTRANSFERASE gene. It is characterized by low… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
High density lipoprotein (HDL) is the major atheroprotective particle in plasma. Recent studies demonstrate that myeloperoxidase… (More)
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Highly Cited
2004
Highly Cited
2004
Lecithin-retinol acyltransferase (LRAT), an enzyme present mainly in the retinal pigmented epithelial cells and liver, converts… (More)
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Highly Cited
2004
Highly Cited
2004
In individuals with type 2 diabetes, metabolic syndrome, and the combined dyslipidemia, cardiovascular risk is increased by a… (More)
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Highly Cited
2001
Highly Cited
2001
The chromophore of the visual pigments, 11-cis retinal, is derived from vitamin A (all-trans retinol) through a series of… (More)
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2001
2001
Lecithin-cholesterol acetyltransferase (LCAT) is involved in the synthesis of plasma cholesteryl esters and is pivotal in the… (More)
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2001
2001
To evaluate the biochemical and molecular mechanisms leading to glomerulosclerosis and the variable development of… (More)
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Highly Cited
1998
Highly Cited
1998
The enzyme acyl coenzyme A:cholesterol acyltransferase 1 (ACAT1) mediates sterol esterification, a crucial component of… (More)
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Highly Cited
1997
Highly Cited
1997
A subset of patients with high plasma HDL concentration have enhanced rather than reduced atherosclerosis. We have developed a… (More)
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1977
1977
Familial lecithin-cholesterol acyltransferase deficiency is a hereditary disorder of lipid metabolism. Lipid material is… (More)
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Highly Cited
1969
Highly Cited
1969
A WOMAN WITH FAMILIAL PLASMA LECITHIN: cholesterol acyltransferase (L.C.A.T.) deficiency showed, like the other reported cases… (More)
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