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Last Observation Carried Forward Imputation Technique

Known as: LOCF 
The substitution of missing data with the most recent data collected that is not missing.
National Institutes of Health

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2 relations
CDISC ADaM Derivation Type TerminologyClinical Data Interchange Standards Consortium Terminology

Papers overview

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Review
2019
Review
2019
The relationship between fermented foods and depression: A systematic review.
2018
2018
Open-Label Study to Evaluate the Efficacy of Etanercept Treatment in Subjects With Moderate to Severe Plaque Psoriasis Who Have Failed Therapy With Apremilast.
INTRODUCTION Response to etanercept therapy in patients who have failed apremilast therapy has not been well characterized… 
Review
2011
Review
2011
Using SAS® for Modeling and Simulation in Drug Development - A Review and Assessment of Some Available Tools
It is widely recognized that modeling and simulation is a valuable tool that can be used to help understand various… 
2010
2010
Российский регистр Инфликсимаба.Влияние терапии на функциональное состояние больных ревматоидным артритом
Objective. To evaluate the functional state of rheumatoid arthritis (RA) patients receiving Infliximab therapy (IF) in real… 
2009
2009
LOCF: It's More Than Just Carrying Forward
Missing data is part of any clinical study been performed and it’s always a priority for any clinical team on how to deal with it… 
2008
2008
ANALYSIS OF LONGITUDINAL BINARY DATA: AN APPLICATION TO A DISEASE PROCESS
The analysis of longitudinal binary data can be undertaken using any of the three families of models namely, marginal, random… 
Review
2006
Review
2006
Lumbar epidural steroids are not cost effective in sciatica
*This article is free to read on the publisher's website* Background Lumbar Epidural Steroids Injections (ESI’s) have… 
2005
2005
LAST OBSERVATION ANALYSIS IN ANOVA AND ANCOVA
In clinical trials with multiple visits, dropouts often occur and the popula- tion of patients who dropped out may be dieren t… 
2004
2004
Empirical Bayes methods for missing data analysis
Missing data in clinical trials can ruin the significance of test results and violates the Intention To Treat principle… 
2001
2001
ects of a flexible galantamine dose in Alzheimer ’ s disease : a randomised , controlled trial
Objective—To assess the eYcacy and safety of galantamine in Alzheimer’s disease at 3 months using flexible dose escalation…