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Laronidase

Known as: Alpha-L-iduronidase precursor 
National Institutes of Health

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5 ML Laronidase 0.58 MG/ML Injection [Aldurazyme]Alpha-glucosidaseL-IduronidaseMucopolysaccharidosis I

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Aldurazyme

Papers overview

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2019
2019
Clinical trial of laronidase in Hurler syndrome after hematopoietic cell transplantation
Background Mucopolysaccharidosis I (MPS IH) is a lysosomal storage disease treated with hematopoietic cell transplantation (HCT… 
Review
2016
Review
2016
Enzyme replacement therapy with laronidase (Aldurazyme(®)) for treating mucopolysaccharidosis type I.
BACKGROUND Mucopolysaccharidosis type I can be classified as three clinical sub-types; Hurler syndrome, Hurler-Scheie syndrome… 
2016
2016
TCRαβ CD19 depletion in allogeneic haematopoietic stem cell transplantation performed for Hurler syndrome
TCRαβ CD19 depletion in allogeneic haematopoietic stem cell transplantation performed for Hurler syndrome 
2015
2015
Successful pregnancy and breastfeeding in a woman with mucopolysaccharidosis type I while receiving laronidase enzyme replacement. therapy.
The authors describe the first mother-infant pair to complete an on-going, prospective, open-label, Phase 4 trial (ALIU) UU3… 
Review
2012
Review
2012
Laronidase Treatment of Mucopolysaccharidosis I
The lysosomal storage disorder (LSD) mucopolysaccharidosis type I (MPS I, McKusick 25280, Hurler syndrome, Hurler-Scheie syndrome… 
2008
2008
Uptake of a Recombinant Human α- L -Iduronidase (laronidase) by Cultured Fibroblasts and Osteoblasts
To examine the uptake of a recombinant human α-L-iduronidase (laronidase) by cultured fibroblasts from a patient with… 
Review
2008
Review
2008
Laronidase (Aldurazyme): enzyme replacement therapy for mucopolysaccharidosis type I.
BACKGROUND Laronidase (Aldurazyme) is a recombinant formulation of alpha-L-iduronidase, the enzyme deficient in… 
Review
2007
Review
2007
Laronidase for treating mucopolysaccharidosis type I.
Mucopolysaccharidoses are a group of inherited metabolic diseases caused by the absence or deficiency of the lysosomal enzymes… 
2006
2006
Effect of discontinuing of laronidase in a patient with mucopolysaccharidosis type I
SummaryWe present a patient on enzyme replacement therapy who showed rapid deterioration when laronidase was discontinued owing… 
2005
2005
Changes in hair morphology of mucopolysaccharidosis I patients treated with recombinant human α‐L‐iduronidase (laronidase, Aldurazyme)
Mucopolysaccharidoses (MPS) are heritable, metabolic diseases caused by accumulation of mucopolysaccharides (glycosaminoglycans… 
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