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Lapuleucel-T
A cell-based vaccine targets tumors expressing the HER2/neu marker. HER-2/neu is a growth factor receptor, and its overexpression has been associated…
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National Institutes of Health
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Related topics
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2 relations
Narrower (1)
APC 8024
Broader (1)
Cancer Vaccines
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Highly Cited
2009
Highly Cited
2009
A Phase I Trial of Immunotherapy with Lapuleucel-T (APC8024) in Patients with Refractory Metastatic Tumors that Express HER-2/neu
P. Peethambaram
,
M. Melisko
,
+7 authors
John W. Park
Clinical Cancer Research
2009
Corpus ID: 13779224
Purpose: This study aimed to evaluate the safety of, immune response induced by, and efficacy of treatment with lapuleucel-T…
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Highly Cited
2007
Highly Cited
2007
Treatment with autologous antigen-presenting cells activated with the HER-2 based antigen Lapuleucel-T: results of a phase I study in immunologic and clinical activity in HER-2 overexpressing breast…
John W. Park
,
M. Melisko
,
L. Esserman
,
L. Jones
,
Jami B. Wollan
,
R. Sims
Journal of Clinical Oncology
2007
Corpus ID: 23313707
PURPOSE Lapuleucel-T (APC8024), an autologous active cellular immunotherapy, was prepared from peripheral-blood mononuclear cells…
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