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Lanepitant

Known as: N-((R)-2-Indol-3-yl-1-((N-(o-methoxybenzyl)acetamido)methyl)ethyl)(1,4'-bipiperidine)-1'-acetamide 
National Institutes of Health

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LY 303870

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
NK1 receptor antagonists as a new treatment for corneal neovascularization.
PURPOSE To determine whether the inhibition of Substance P (SP) activity can reduce corneal neovascularization (CNV) by means of… 
Highly Cited
2001
Highly Cited
2001
Lanepitant, an NK-1 Antagonist, in Migraine Prevention
Lanepitant, a potent non-peptide neurokinin-1 receptor antagonist, inhibits neurogenic dural inflammation, and may have a role in… 
2001
2001
Dose-Response Study of the Analgesic Effect of Lanepitant in Patients with Painful Diabetic Neuropathy
Lanepitant is effective in the formalin analgesic model suggesting efficacy in painful neuropathy. This study was designed to… 
Review
2000
Review
2000
Current and Emerging Second‐Generation Triptans in Acute Migraine Therapy: A Comparative Review
Sterile neurogenic inflammation within cephalic tissue, involving vasodilation and plasma protein extravasation, has been… 
Highly Cited
2000
Highly Cited
2000
Study of the analgesic effect of lanepitant in patients with osteoarthritis pain
Lanepitant selectively blocks substance P binding to the neurokinin‐1 receptor, preventing neurogenic inflammation and pain… 
1999
1999
Lanepitant, An NK‐1 Antagonist, in Migraine Prophylaxis
1999
1999
Lanepitant, an NK‐1 antagonist, in painful diabetic neuropathy
Highly Cited
1997
Highly Cited
1997
Ineffectiveness of Neurokinin-1 Antagonist in Acute Migraine
Lanepitant is a high-affinity selective neurokinin-1 receptor (NK-1) and is effective in the dural inflammation model of acute… 
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