LY686017
National Institutes of Health
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NK-1 receptor antagonists have shown potential for the clinical treatment of chemotherapy-induced nausea and vomiting, depression…
The neurokinin-1 (NK-1) antagonist LY686017 showed activity in preclinical anxiety models. The clinical development of LY686017…
Conjugation allows bacteria to acquire genes for antibiotic resistance, novel virulence attributes, and alternative metabolic…
Alcohol dependence is a major public health challenge in need of new treatments. As alcoholism evolves, stress systems in the…
: RO simulations with the human PKRO model confirmed the dose of 50 mg QD for POC studies: RO predictions were > 90% as a mean…