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LY2112688

 
National Institutes of Health

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Broader (1)

Peptides

Papers overview

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2020
2020
Intestine-selective reduction of Gcg expression reveals the importance of the distal gut for GLP-1 secretion
Objective Glucagon-like peptide-1 is a nutrient-sensitive hormone secreted from enteroendocrine L cells within the small and… Expand
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2015
2015
Temporal cAMP Signaling Selectivity by Natural and Synthetic MC4R Agonists.
The melanocortin-4 receptor (MC4R) is a G protein-coupled receptor expressed in the brain, where it controls energy balance… Expand
2015
2015
Melanocortin agonists stimulate lipolysis in human adipose tissue explants but not in adipocytes
BackgroundThe central melanocortin system is broadly involved in the regulation of mammalian nutrient utilization. However, the… Expand
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Highly Cited
2013
Highly Cited
2013
Chronic Treatment With a Melanocortin-4 Receptor Agonist Causes Weight Loss, Reduces Insulin Resistance, and Improves Cardiovascular Function in Diet-Induced Obese Rhesus Macaques
The melanocortin-4 receptor (MC4R) is well recognized as an important mediator of body weight homeostasis. Activation of MC4R… Expand
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