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LY 303511

Known as: LY-303511, LY303511 
National Institutes of Health

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ChromonesPiperazines

Papers overview

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2011
2011
' s personal copy The Phosphatidylinositol 3-kinase ( PI 3 K ) inhibitor LY 294002 modulates cytokine expression in macrophages via p 50 nuclear factor kappa B inhibition , in a PI 3 K-independent…
The Phosphatidylinositol 3-kinase (PI3K) inhibitor, LY294002 (LY2), has been previously reported to inhibit nuclear factor kB… 
2009
2009
Bone marrow mesenchymal stem cells undergo nemosis and induce keratinocyte wound healing utilizing the HGF/c‐Met/PI3K pathway
We previously showed cell–cell contacts of human dermal fibroblasts to induce expression of the hepatocyte growth factor/scatter… 
2009
2009
COMPUTATIONAL MODELING OF PATHWAY DYNAMICS FOR DETECTING DRUG EFFECTS : PARADOXICAL EFFECTS OF LY 303511 ON TRAIL-INDUCED APOPTOSIS
Yuan Shi, Simi M. Varghese, Sinong Huang, Jacob White, Shazib Pervaiz, Lisa Tucker-Kellogg 1 Singapore-MIT Alliance, E4-04-10, 4… 
2008
2008
GM3 Signals Regulating TNF-Alpha Expression Are Mediated by Rictor and Arhgdib in Mouse Melanoma B16 Cells
Objective: We have previously shown GM3 to positively regulate TNF-α expression via a PI3K/Akt pathway in mouse melanoma B16… 
2008
2008
LY294002 inhibits glucocorticoid-induced COX-2 gene expression in cardiomyocytes through a phosphatidylinositol 3 kinase-independent mechanism.
2008
2008
Hemoglobin neurotoxicity is attenuated by inhibitors of the protein kinase CK2 independent of heme oxygenase activity.
The heme oxygenase (HO) enzymes catalyze the rate-limiting step of heme breakdown, and may accelerate oxidative injury to neurons… 
2007
2007
A study on the anti tumor activity of LY303511, an inactive analogue of a P13k inhibitor, LY294002
2006
2006
Enhancement of cytokine-mediated NF-kappaB activation by phosphatidylinositol 3-kinase inhibitors in monocytic cells.
2005
2005
3-Kinase-Akt Pathway Production Independent of the Phosphoinositide PeroxideDrug-Induced Apoptosis via Intracellular Hydrogen LY 294002 and LY 303511 Sensitize Tumor Cells
The phosphoinositide 3-kinase (PI3K)-Akt pathway is constitutively active in many tumors, and inhibitors of this prosurvival… 
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