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LY 303511
Known as:
LY-303511
, LY303511
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Chromones
Piperazines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
The commonly used PI3-kinase probe LY294002 is an inhibitor of BET bromodomains.
A. Dittmann
,
Thilo Werner
,
+9 authors
G. Drewes
ACS chemical biology
2014
Corpus ID: 206871269
A commonly used small-molecule probe in cell-signaling research is the phosphoinositide 3-kinase inhibitor LY294002. Quantitative…
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Highly Cited
2009
Highly Cited
2009
Polar bacterial invasion and translocation of Streptococcus suis across the blood‐cerebrospinal fluid barrier in vitro
T. Tenenbaum
,
T. Papandreou
,
+7 authors
H. Schroten
Cellular microbiology
2009
Corpus ID: 27072380
Previous experimental studies in a standard Transwell culture system have shown Streptococcus suis ability to compromise barrier…
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Highly Cited
2007
Highly Cited
2007
Role of reactive oxygen species in protein degradation in murine myotubes induced by proteolysis-inducing factor and angiotensin II.
S. Russell
,
H. Eley
,
M. Tisdale
Cellular signalling
2007
Corpus ID: 36609124
Highly Cited
2006
Highly Cited
2006
Insulin induces heme oxygenase‐1 through the phosphatidylinositol 3‐kinase/Akt pathway and the Nrf2 transcription factor in renal cells
E. Harrison
,
S. McNally
,
L. Devey
,
O. J. Garden
,
J. Ross
,
S. Wigmore
The FEBS journal
2006
Corpus ID: 24100825
Heme oxygenase‐1 catalyzes the breakdown of heme and is protective in models of kidney transplantation. In this study we describe…
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Highly Cited
2005
Highly Cited
2005
LY294002 and LY303511 sensitize tumor cells to drug-induced apoptosis via intracellular hydrogen peroxide production independent of the phosphoinositide 3-kinase-Akt pathway.
T. W. Poh
,
S. Pervaiz
Cancer research
2005
Corpus ID: 14313106
The phosphoinositide 3-kinase (PI3K)-Akt pathway is constitutively active in many tumors, and inhibitors of this prosurvival…
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Highly Cited
2005
Highly Cited
2005
Insulin Stimulates Postsynaptic Density-95 Protein Translation via the Phosphoinositide 3-Kinase-Akt-Mammalian Target of Rapamycin Signaling Pathway*
Cheng-Che Lee
,
Chiung‐Chun Huang
,
Mei-Ying Wu
,
K. Hsu
Journal of Biological Chemistry
2005
Corpus ID: 6396110
Insulin receptors are highly enriched at neuronal synapses, but whose function remains unclear. Here we present evidence that…
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Highly Cited
2005
Highly Cited
2005
Regulation of cholinergic gene expression by nerve growth factor depends on the phosphatidylinositol‐3′‐kinase pathway
B. Madziar
,
I. López-Coviella
,
V. Zemelko
,
B. Berse
Journal of neurochemistry
2005
Corpus ID: 22736208
Nerve growth factor (NGF) exerts anti‐apoptotic, trophic and differentiating actions on sympathetic neurons and cholinergic cells…
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Highly Cited
2003
Highly Cited
2003
The phosphatidylinositol 3‐kinase inhibitor LY294002 potently blocks Kv currents via a direct mechanism
W. El-kholy
,
P. MacDonald
,
+6 authors
Michael B. Wheeler
FASEB journal : official publication of the…
2003
Corpus ID: 24976669
Voltage‐dependent K+ (Kv) channels negatively regulate Ca2+ entry into pancreatic β‐cells by repolarizing glucose‐stimulated…
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Highly Cited
2000
Highly Cited
2000
Phosphatidylinositol 3-Kinase Activation and Interaction with Focal Adhesion Kinase in Escherichia coli K1 Invasion of Human Brain Microvascular Endothelial Cells*
M. Reddy
,
N. Prasadarao
,
C. Wass
,
K. Kim
The Journal of Biological Chemistry
2000
Corpus ID: 41558821
Invasion of brain microvascular endothelial cells (BMEC) is a prerequisite for successful crossing of the blood-brain barrier by…
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Highly Cited
1995
Highly Cited
1995
Antagonists of phosphatidylinositol 3-kinase block activation of several novel protein kinases in neutrophils
J. Ding
,
CJ Vlahos
,
R. Liu
,
Rf Brown
,
J. Badwey
The Journal of Biological Chemistry
1995
Corpus ID: 21633220
Several novel protein kinases are known to be rapidly activated in neutrophils stimulated with the chemoattractant fMet-Leu-Phe…
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