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LY 290181

Known as: LY-290181, LY290181 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-1998
01219961998

Related topics

Related topics

2 relations

Broader (2)

NaphthalenesPyrans

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
LY 290181
Naphthalenes
Pyrans

Papers overview

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1998
1998
Polyphenol-mediated inhibition of AP-1 transactivating activity may slow cancer growth by impeding angiogenesis and tumor invasiveness.
Certain polyphenols, capable of activating transcription via antioxidant response elements, potently induce Fra-1/Fra-2, thereby… (More)
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1997
1997
Suppression of microtubule dynamics by LY290181. A potential mechanism for its antiproliferative action.
LY290181, 2-amino-4-(3-pyridyl)-4H-naphtho(1,2-b)pyran-3-carbonitrile, is a potent antiproliferative compound that blocks cells… (More)
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1997
1997
Inhibition of mitosis and microtubule function through direct tubulin binding by a novel antiproliferative naphthopyran LY290181.
The mechanism of action of a novel antiproliferative compound LY290181 [2-amino-4-(3-pyridyl)-4H-naphtho(1,2-b)pyran-3… (More)
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1996
1996
LY290181, an inhibitor of diabetes-induced vascular dysfunction, blocks protein kinase C-stimulated transcriptional activation through inhibition of transcription factor binding to a phorbol response…
Previous studies have shown that high glucose levels and diabetes induce an elevation in protein kinase C (PKC) activity in… (More)
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1996
1996
Inhibition of vascular smooth muscle cell proliferation and arterial intimal thickening by a novel antiproliferative naphthopyran.
Smooth muscle cell proliferation plays an important role in neointimal thickening after vascular injury and may contribute to… (More)
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