Skip to search formSkip to main contentSkip to account menu

LXT-101

National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Oligopeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Release Characteristics In Vitro and In Vivo of In Situ Gels for a Novel Peptide Compared with Low-Molecular-Weight Hydrophilic Drug.
BACKGROUND The thermo-sensitive in situ gels based on copolymers are attractive as an injectable drug delivery carriers for… 
2013
2013
Oral delivery of oil-based formulation for a novel synthetic cationic peptide of GnRH (gonadotropin-releasing hormone) antagonist for prostate cancer treatment.
2011
2011
Multivesicular liposome (MVL) sustained delivery of a novel synthetic cationic GnRH antagonist for prostate cancer treatment
Objectives  Multivesicular liposomes (MVLs) are often used as an appropriate carrier for delivering peptides due to high drug… 
2011
2011
In-vitro/in-vivo studies of the biodegradable poly-(d,l-lactide-co-glycolide) microspheres of a novel luteinizing hormone-releasing hormone antagonist for prostate cancer treatment
The introduction of luteinizing hormone-releasing hormone (LHRH) analogs and their antagonists is revolutionizing the treatment… 
2009
2009
[Multivesicular liposome sustained delivery of a novel synthetic electropositive Positive GnRH antagonist LXT-101: preparation and in vitro evaluation].
Using a simple method to determine the interaction between peptide and lipid bilayer and then deciding how to modify formulation… 
2008
2008
[Determination of decapeptide LXT-101 in plasma by HPLC-MS/MS and its pharmacokinetics in Beagle dogs].
This paper developed a sensitive and specific liquid chromatography-electrospray ionization mass spectrometry (HPLC-MS/MS) method… 
2006
2006
Biodegradable PLGA microspheres as a sustained release system for a new luteinizing hormone-releasing hormone (LHRH) antagonist.
A sustained release poly(DL-lactide-co-glycolide) (PLGA) microsphere delivery system to treat prostate cancer for a luteinizing… 
2006
2006
In vivo characterization of a novel GnRH (gonadotropin-releasing hormone) antagonist, LXT-101, in normal male rats
2005
2005
Biological characterization of a novel and potent gonadotropin releasing hormone （GnRH） antagonist LXT-101
AIM The biological characterization of LXT-101 was investigated in vivo using intact male rats and nude mice bearing xenografts… 
2004
2004
Pharmacological profile of a new and potent gonadotropin releasing hormone antagonist LXT-101
AIM: To investigate the pharmacological effect of LXT-101 on serum testosterone level in intact male rats. METHODS: Ratswere… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)