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LXT-101
National Institutes of Health
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Broader (1)
Oligopeptides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Release Characteristics In Vitro and In Vivo of In Situ Gels for a Novel Peptide Compared with Low-Molecular-Weight Hydrophilic Drug.
Guiying Zhang
,
Jie Hu
,
+4 authors
Dongqin Quan
Current Drug Delivery
2017
Corpus ID: 13118458
BACKGROUND The thermo-sensitive in situ gels based on copolymers are attractive as an injectable drug delivery carriers for…
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2013
2013
Oral delivery of oil-based formulation for a novel synthetic cationic peptide of GnRH (gonadotropin-releasing hormone) antagonist for prostate cancer treatment.
Guiying Zhang
,
Tao Wang
,
Lijun Gao
,
Dongqin Quan
International journal of pharmaceutics
2013
Corpus ID: 5305368
2011
2011
Multivesicular liposome (MVL) sustained delivery of a novel synthetic cationic GnRH antagonist for prostate cancer treatment
Tao Wang
,
Lijun Gao
,
Dongqin Quan
The Journal of pharmacy and pharmacology
2011
Corpus ID: 42363364
Objectives Multivesicular liposomes (MVLs) are often used as an appropriate carrier for delivering peptides due to high drug…
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2011
2011
In-vitro/in-vivo studies of the biodegradable poly-(d,l-lactide-co-glycolide) microspheres of a novel luteinizing hormone-releasing hormone antagonist for prostate cancer treatment
Lina Du
,
X. Mei
,
Chenyun Wang
,
Xin Li
,
Fucheng Zhang
,
Yiguang Jin
Anti-Cancer Drugs
2011
Corpus ID: 9865869
The introduction of luteinizing hormone-releasing hormone (LHRH) analogs and their antagonists is revolutionizing the treatment…
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2009
2009
[Multivesicular liposome sustained delivery of a novel synthetic electropositive Positive GnRH antagonist LXT-101: preparation and in vitro evaluation].
Tao Wang
,
Dongqin Quan
Yao xue xue bao = Acta pharmaceutica Sinica
2009
Corpus ID: 19386558
Using a simple method to determine the interaction between peptide and lipid bilayer and then deciding how to modify formulation…
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2008
2008
[Determination of decapeptide LXT-101 in plasma by HPLC-MS/MS and its pharmacokinetics in Beagle dogs].
Ai-ying Kong
,
Zhen-qing Zhang
,
+4 authors
J. Ruan
Yao xue xue bao = Acta pharmaceutica Sinica
2008
Corpus ID: 44848331
This paper developed a sensitive and specific liquid chromatography-electrospray ionization mass spectrometry (HPLC-MS/MS) method…
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2006
2006
Biodegradable PLGA microspheres as a sustained release system for a new luteinizing hormone-releasing hormone (LHRH) antagonist.
Lina Du
,
Junping Cheng
,
Q. Chi
,
Jiankun Qie
,
Yan Liu
,
X. Mei
Chemical and pharmaceutical bulletin
2006
Corpus ID: 30440647
A sustained release poly(DL-lactide-co-glycolide) (PLGA) microsphere delivery system to treat prostate cancer for a luteinizing…
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2006
2006
In vivo characterization of a novel GnRH (gonadotropin-releasing hormone) antagonist, LXT-101, in normal male rats
Xiaoli Chi
,
Wenxia Zhou
,
Jun-ping Cheng
,
Yongxiang Zhang
,
Keliang Liu
Regulatory Peptides
2006
Corpus ID: 20415828
2005
2005
Biological characterization of a novel and potent gonadotropin releasing hormone (GnRH) antagonist LXT-101
Xiao-liCHI
,
Wen-xiaZHOU
,
Jun-pingCHENG
,
Yong-xiangZHANG
,
Ke-liangLIU
2005
Corpus ID: 82424795
AIM The biological characterization of LXT-101 was investigated in vivo using intact male rats and nude mice bearing xenografts…
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2004
2004
Pharmacological profile of a new and potent gonadotropin releasing hormone antagonist LXT-101
Xiao-liCHI
,
Wen-xiaZHOU
,
Jun-pingCHENG
,
Yong-xiangZHANG
,
Ke-liangLIU
2004
Corpus ID: 68559856
AIM: To investigate the pharmacological effect of LXT-101 on serum testosterone level in intact male rats. METHODS: Ratswere…
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