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LXR 623

Known as: LXR-623, LXR623 
National Institutes of Health

Papers overview

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2019
2019
Growing evidence indicates that clear cell renal cell carcinoma (ccRCC) is a metabolism-related disease. Changes in fatty acid… Expand
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2019
2019
LXR-623 (WAY-252623), a liver X receptor agonist, reduces atherosclerotic plaque progression and remarkably inhibits the… Expand
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2019
2019
Cholesterol is a pivotal factor for cancer cells to entertain their relentless growth. In this case, we provide a novel strategy… Expand
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Highly Cited
2016
Highly Cited
2016
Small-molecule inhibitors targeting growth factor receptors have failed to show efficacy for brain cancers, potentially due to… Expand
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Review
2012
Review
2012
Liver X receptors (LXR) are members of the nuclear receptor family. As activated transcription factors, their putative… Expand
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2012
2012
AIMS The aim of this study was to investigate the effects of liver X receptors (LXRs)-β preferential activation by LXR-623 (WAY… Expand
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Review
2010
Review
2010
Importance of the field: Liver X receptors (LXRs) are ligand activated transcription factors involved in cholesterol metabolism… Expand
Highly Cited
2009
Highly Cited
2009
Liver X‐receptor (LXR) agonists have been postulated to enhance reverse cholesterol transport (RCT), a process believed to… Expand
Highly Cited
2009
Highly Cited
2009
Liver X receptors (LXRs) are ligand-activated transcription factors that coordinate regulation of gene expression involved in… Expand
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2008
2008
BackgroundLXRs (Liver X Receptor α and β) are nuclear receptors that act as ligand-activated transcription factors. LXR… Expand
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