Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 209,920,998 papers from all fields of science
Search
Sign In
Create Free Account
LXR 623
Known as:
LXR-623
, LXR623
National Institutes of Health
Create Alert
Alert
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Targeting the transcription factor receptor LXR to treat clear cell renal cell carcinoma: agonist or inverse agonist?
Guangzhen Wu
,
Qinglian Wang
,
+4 authors
Q. Xia
Cell Death and Disease
2019
Corpus ID: 167220369
Growing evidence indicates that clear cell renal cell carcinoma (ccRCC) is a metabolism-related disease. Changes in fatty acid…
Expand
2019
2019
The LXR-623-induced long non-coding RNA LINC01125 suppresses the proliferation of breast cancer cells via PTEN/AKT/p53 signaling pathway
Weijun Wan
,
Y. Hou
,
Ke Wang
,
Yue Cheng
,
X. Pu
,
Xiu-feng Ye
Cell Death and Disease
2019
Corpus ID: 76660622
LXR-623 (WAY-252623), a liver X receptor agonist, reduces atherosclerotic plaque progression and remarkably inhibits the…
Expand
2019
2019
SIRT2 plays a novel role on progesterone, estradiol and testosterone synthesis via PPARs/LXRα pathways in bovine ovarian granular cells
Dejun Xu
,
Huanshan He
,
+6 authors
Qingwang Li
Journal of Steroid Biochemistry and Molecular…
2019
Corpus ID: 51627633
2019
2019
Activation of LXR Receptors and Inhibition of TRAP1 Causes Synthetic Lethality in Solid Tumors
T. Nguyen
,
C. T. Ishida
,
+4 authors
M. Siegelin
Cancers
2019
Corpus ID: 184484431
Cholesterol is a pivotal factor for cancer cells to entertain their relentless growth. In this case, we provide a novel strategy…
Expand
Highly Cited
2016
Highly Cited
2016
An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers.
Genaro R. Villa
,
Jonathan J. Hulce
,
+24 authors
P. Mischel
Cancer Cell
2016
Corpus ID: 28501171
Review
2012
Review
2012
Selective liver X receptor modulators (SLiMs): What use in human health?
E. Viennois
,
K. Mouzat
,
J. Dufour
,
L. Morel
,
J. Lobaccaro
,
S. Baron
Molecular and Cellular Endocrinology
2012
Corpus ID: 25343063
Review
2010
Review
2010
Liver X receptor modulators: a review of recently patented compounds (2007 – 2009)
Xiaolin Li
,
V. Yeh
,
V. Molteni
Expert Opinion on Therapeutic Patents
2010
Corpus ID: 8979114
Importance of the field: Liver X receptors (LXRs) are ligand activated transcription factors involved in cholesterol metabolism…
Expand
Highly Cited
2009
Highly Cited
2009
Safety, Pharmacokinetics, and Pharmacodynamics of Single Doses of LXR‐623, a Novel Liver X‐Receptor Agonist, in Healthy Participants
A. Katz
,
C. Udata
,
+5 authors
Xu Meng
Journal of clinical pharmacology
2009
Corpus ID: 33412055
Liver X‐receptor (LXR) agonists have been postulated to enhance reverse cholesterol transport (RCT), a process believed to…
Expand
Highly Cited
2009
Highly Cited
2009
LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse[S]
E. Quinet
,
M. Basso
,
+17 authors
G. Vlasuk
Journal of Lipid Research
2009
Corpus ID: 486812
Liver X receptors (LXRs) are ligand-activated transcription factors that coordinate regulation of gene expression involved in…
Expand
2008
2008
Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells
E. DiBlasio-Smith
,
M. Arai
,
+16 authors
E. Lavallie
Journal of Translational Medicine
2008
Corpus ID: 1177062
BackgroundLXRs (Liver X Receptor α and β) are nuclear receptors that act as ligand-activated transcription factors. LXR…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE