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LXR 623

Known as: LXR-623, LXR623 
 
National Institutes of Health

Papers overview

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2019
2019
LXR-623 (WAY-252623), a liver X receptor agonist, reduces atherosclerotic plaque progression and remarkably inhibits the… Expand
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2019
2019
Growing evidence indicates that clear cell renal cell carcinoma (ccRCC) is a metabolism-related disease. Changes in fatty acid… Expand
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2019
2019
Cholesterol is a pivotal factor for cancer cells to entertain their relentless growth. In this case, we provide a novel strategy… Expand
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2019
2019
SIRT2 has been shown to possess NAD+-dependent deacetylase and desuccinylase enzymatic activities, it also regulates metabolism… Expand
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Highly Cited
2016
Highly Cited
2016
Small-molecule inhibitors targeting growth factor receptors have failed to show efficacy for brain cancers, potentially due to… Expand
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Review
2015
Review
2015
Dyslipidaemia is a major risk factor for cardiovascular diseases. Pharmacological lowering of LDL-C levels using statins reduces… Expand
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2012
2012
AIMS The aim of this study was to investigate the effects of liver X receptors (LXRs)-β preferential activation by LXR-623 (WAY… Expand
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Highly Cited
2009
Highly Cited
2009
Liver X-receptor (LXR) agonists have been postulated to enhance reverse cholesterol transport (RCT), a process believed to… Expand
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Highly Cited
2009
Highly Cited
2009
Liver X receptors (LXRs) are ligand-activated transcription factors that coordinate regulation of gene expression involved in… Expand
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2008
2008
BackgroundLXRs (Liver X Receptor α and β) are nuclear receptors that act as ligand-activated transcription factors. LXR… Expand
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