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LRRC4 gene
Known as:
leucine rich repeat containing 4
, NAG14
, LRRC4
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National Institutes of Health
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LRRC1 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Novel Therapy for Glioblastoma Multiforme by Restoring LRRC4 in Tumor Cells: LRRC4 Inhibits Tumor-Infitrating Regulatory T Cells by Cytokine and Programmed Cell Death 1-Containing Exosomes
Peiyao Li
,
Jianbo Feng
,
+10 authors
Minghua Wu
Front. Immunol.
2017
Corpus ID: 1304904
Glioblastoma multiforme (GBM) is a heterogeneous malignant brain tumor, the pathological incidence of which induces the…
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Highly Cited
2014
Highly Cited
2014
Disturbing miR-182 and -381 Inhibits BRD7 Transcription and Glioma Growth by Directly Targeting LRRC4
Hailin Tang
,
Zeyou Wang
,
Qing Liu
,
Xiaoping Liu
,
Minghua Wu
,
Guiyuan Li
PloS one
2014
Corpus ID: 16010993
Inactivated LRRC4 has been clinically detected in gliomas, and promoter hypermethylation has been implicated as the mechanism of…
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Highly Cited
2011
Highly Cited
2011
Interaction of hsa-miR-381 and glioma suppressor LRRC4 is involved in glioma growth
Hailin Tang
,
Xiaoping Liu
,
+10 authors
Gui-yuan Li
Brain Research
2011
Corpus ID: 24024869
2011
2011
LRRC4 inhibits the proliferation of human glioma cells by modulating the expression of STMN1 and microtubule polymerization
Rong Wang
,
Zeyou Wang
,
+6 authors
Guiyuan Li
Journal of cellular biochemistry
2011
Corpus ID: 25665782
LRRC4 is a tumor suppressor of glioma, and it is epigenetically inactivated commonly in glioma. Our previous study has shown that…
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2008
2008
Promoter Hypermethylation-mediated Inactivation of LRRC4 in Gliomas
Zuping Zhang
,
Dan Li
,
+7 authors
Gui-yuan Li
BMC Molecular Biology
2008
Corpus ID: 304726
BackgroundLeucine-rich repeat C4 protein (LRRC4) is a new member of the leucine-rich repeat (LRR) superfamily. It is not only a…
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Highly Cited
2006
Highly Cited
2006
LRRC4, a putative tumor suppressor gene, requires a functional leucine-rich repeat cassette domain to inhibit proliferation of glioma cells in vitro by modulating the extracellular signal-regulated…
Minghua Wu
,
Chen Huang
,
+14 authors
Gui-yuan Li
Molecular biology of the cell
2006
Corpus ID: 12940518
We have previously reported that the LRRC4 gene, which contains a conserved leucine-rich repeat (LRR) cassette and an…
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2006
2006
LRRC4 controls in vitro invasion of glioblastoma cells through inhibiting RPTP-zeta expression
Minghua Wu
,
Kai Gan
,
+6 authors
Gui-yuan Li
Journal of Neuro-Oncology
2006
Corpus ID: 30590797
LRRC4 (leucine rich repeat containing 4), a novel member of LRP (Leucine-rich repeat protein) superfamily, contains a conserved…
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2005
2005
Expression and functional characterization of LRRC4, a novel brain‐specific member of the LRR superfamily
Qiu-hong Zhang
,
Jie-ru Wang
,
+11 authors
Gui-yuan Li
FEBS letters
2005
Corpus ID: 19888187
2005
2005
Study of a novel brain relatively specific gene LRRC4 involved in glioma tumorigenesis suppression using the Tet-on system.
Qiu-hong Zhang
,
Li-li Wang
,
+7 authors
Gui-yuan Li
Acta biochimica et biophysica Sinica
2005
Corpus ID: 621431
LRRC4 is a novel relatively specific gene, which displays significant down-regulation in primary brain tumor biopsies and has the…
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2003
2003
Expression of LRRC4 has the potential to decrease the growth rate and tumorigenesis of glioblastoma cell line U251.
Jie-ru Wang
,
Xiao-Ling Li
,
+5 authors
Gui-yuan Li
Ai zheng = Aizheng = Chinese journal of cancer
2003
Corpus ID: 9821414
BACKGROUND & OBJECTIVE LRRC4 is a novel gene that the author has identified recently, which displayed significant downregulation…
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