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LRRC4 gene

Known as: leucine rich repeat containing 4, NAG14, LRRC4 
National Institutes of Health

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Related topics

1 relation
LRRC1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Novel Therapy for Glioblastoma Multiforme by Restoring LRRC4 in Tumor Cells: LRRC4 Inhibits Tumor-Infitrating Regulatory T Cells by Cytokine and Programmed Cell Death 1-Containing Exosomes
Glioblastoma multiforme (GBM) is a heterogeneous malignant brain tumor, the pathological incidence of which induces the… 
Highly Cited
2014
Highly Cited
2014
Disturbing miR-182 and -381 Inhibits BRD7 Transcription and Glioma Growth by Directly Targeting LRRC4
Inactivated LRRC4 has been clinically detected in gliomas, and promoter hypermethylation has been implicated as the mechanism of… 
Highly Cited
2011
Highly Cited
2011
Interaction of hsa-miR-381 and glioma suppressor LRRC4 is involved in glioma growth
2011
2011
LRRC4 inhibits the proliferation of human glioma cells by modulating the expression of STMN1 and microtubule polymerization
LRRC4 is a tumor suppressor of glioma, and it is epigenetically inactivated commonly in glioma. Our previous study has shown that… 
2008
2008
Promoter Hypermethylation-mediated Inactivation of LRRC4 in Gliomas
BackgroundLeucine-rich repeat C4 protein (LRRC4) is a new member of the leucine-rich repeat (LRR) superfamily. It is not only a… 
Highly Cited
2006
Highly Cited
2006
LRRC4, a putative tumor suppressor gene, requires a functional leucine-rich repeat cassette domain to inhibit proliferation of glioma cells in vitro by modulating the extracellular signal-regulated…
We have previously reported that the LRRC4 gene, which contains a conserved leucine-rich repeat (LRR) cassette and an… 
2006
2006
LRRC4 controls in vitro invasion of glioblastoma cells through inhibiting RPTP-zeta expression
LRRC4 (leucine rich repeat containing 4), a novel member of LRP (Leucine-rich repeat protein) superfamily, contains a conserved… 
2005
2005
Expression and functional characterization of LRRC4, a novel brain‐specific member of the LRR superfamily
2005
2005
Study of a novel brain relatively specific gene LRRC4 involved in glioma tumorigenesis suppression using the Tet-on system.
LRRC4 is a novel relatively specific gene, which displays significant down-regulation in primary brain tumor biopsies and has the… 
2003
2003
Expression of LRRC4 has the potential to decrease the growth rate and tumorigenesis of glioblastoma cell line U251.
BACKGROUND & OBJECTIVE LRRC4 is a novel gene that the author has identified recently, which displayed significant downregulation… 
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