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LRRC4 gene

Known as: leucine rich repeat containing 4, NAG14, LRRC4 
 
National Institutes of Health

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Related topics

1 relation
LRRC1 gene

Papers overview

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2014
2014
Disturbing miR-182 and -381 Inhibits BRD7 Transcription and Glioma Growth by Directly Targeting LRRC4
Inactivated LRRC4 has been clinically detected in gliomas, and promoter hypermethylation has been implicated as the mechanism of… Expand
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2013
2013
Gene expression profiling of non-hodgkin lymphomas.
BACKGROUND Chromosomal translocations are genetic aberrations associated with specific non-Hodgkin lymphoma (NHL) subtypes. This… Expand
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Highly Cited
2011
Highly Cited
2011
Interaction of hsa-miR-381 and glioma suppressor LRRC4 is involved in glioma growth
LRRC4 is not only a brain-specific gene, but it has also been identified as a tumor suppressor gene for glioma. Promoter… Expand
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2011
2011
LRRC4 inhibits the proliferation of human glioma cells by modulating the expression of STMN1 and microtubule polymerization.
LRRC4 is a tumor suppressor of glioma, and it is epigenetically inactivated commonly in glioma. Our previous study has shown that… Expand
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2008
2008
Promoter Hypermethylation-mediated Inactivation of LRRC4 in Gliomas
BackgroundLeucine-rich repeat C4 protein (LRRC4) is a new member of the leucine-rich repeat (LRR) superfamily. It is not only a… Expand
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2006
2006
LRRC4, a putative tumor suppressor gene, requires a functional leucine-rich repeat cassette domain to inhibit proliferation of glioma cells in vitro by modulating the extracellular signal-regulated…
We have previously reported that the LRRC4 gene, which contains a conserved leucine-rich repeat (LRR) cassette and an… Expand
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2006
2006
LRRC4 controls in vitro invasion of glioblastoma cells through inhibiting RPTP-zeta expression
LRRC4 (leucine rich repeat containing 4), a novel member of LRP (Leucine-rich repeat protein) superfamily, contains a conserved… Expand
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2005
2005
Expression and functional characterization of LRRC4, a novel brain-specific member of the LRR superfamily.
LRRC4, a novel member of LRR superfamily thought to be involved in development and tumorigenesis of the nervous tissue, has the… Expand
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2005
2005
Study of a novel brain relatively specific gene LRRC4 involved in glioma tumorigenesis suppression using the Tet-on system.
LRRC4 is a novel relatively specific gene, which displays significant down-regulation in primary brain tumor biopsies and has the… Expand
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2003
2003
Expression of LRRC4 has the potential to decrease the growth rate and tumorigenesis of glioblastoma cell line U251.
BACKGROUND & OBJECTIVE LRRC4 is a novel gene that the author has identified recently, which displayed significant downregulation… Expand
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