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LOXILAN

National Institutes of Health

Papers overview

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2010
2010
一种碘昔兰中间体的制备方法,以5-硝基-N-(2-羟基乙基)-间甲酰胺苯甲酸为起始原料,依次与甲醇进行甲酯化反应、与3-氨基-1,2-丙二醇在甲醇溶液中进行酰胺化反应、在水溶液中铁酸还原后加一氯化碘碘化反应,以乙酸酐进行乙酰化反应,再氨水水解得5…