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LOX gene
Known as:
LOX
, LYSYL OXIDASE
, Lysyl Oxidase Gene
This gene plays a role in cross-linking extracellular matrix proteins.
National Institutes of Health
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Related topics
Related topics
6 relations
Morphogenesis
Oxidation-Reduction
Protein-Lysine 6-Oxidase
lysyl oxidase activity
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
The Formation of lysine tyrosylquinone (LTQ) is a self-processing reaction. Expression and characterization of a Drosophila lysyl oxidase.
J. Bollinger
,
Doreen E. Brown
,
D. Dooley
Biochemistry
2005
Corpus ID: 43101494
Recent work in our laboratory has established methods for the expression and purification of a recombinant form of Drosophila…
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Highly Cited
2000
Highly Cited
2000
Lysyl Oxidase Activates the Transcription Activity of Human Collagene III Promoter
M. Giampuzzi
,
G. Botti
,
+5 authors
A. Di Donato
Journal of Biological Chemistry
2000
Corpus ID: 19274308
Lysyl oxidase is an extracellular enzyme that controls the maturation of collagen and elastin. Lysyl oxidase and collagen III…
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Highly Cited
1998
Highly Cited
1998
Reduced lysyl oxidase messenger RNA levels in experimental and human prostate cancer.
C. Ren
,
G. Yang
,
T. Timme
,
T. Wheeler
,
T. Thompson
Cancer Research
1998
Corpus ID: 22696036
To identify genes associated with prostate cancer progression, we developed a strategy involving the use of differential display…
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Highly Cited
1996
Highly Cited
1996
Identification of the lysyl oxidase gene as target of the antioncogenic transcription factor, IRF-1, and its possible role in tumor suppression.
R. Tan
,
T. Taniguchi
,
H. Harada
Cancer Research
1996
Corpus ID: 43266913
The transcriptional activator IFN regulatory factor 1 (IRF-1) and its antagonistic repressor IRF-2 are regulators of the IFN…
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Highly Cited
1995
Highly Cited
1995
The proteolytic processing site of the precursor of lysyl oxidase.
A. Cronshaw
,
L. Fothergill-Gilmore
,
D. Hulmes
Biochemical Journal
1995
Corpus ID: 24399007
The precise cleavage site of the N-terminal propeptide region of the precursor of lysyl oxidase has not yet been established, due…
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Highly Cited
1994
Highly Cited
1994
Regulation of lysyl oxidase expression in lung fibroblasts by transforming growth factor-beta 1 and prostaglandin E2.
A. Boak
,
R. Roy
,
+4 authors
H. Kagan
American Journal of Respiratory Cell and…
1994
Corpus ID: 10871903
The regulation of lysyl oxidase produced by cultured, lipid-enriched, neonatal rat lung fibroblasts was explored. The presence of…
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Highly Cited
1993
Highly Cited
1993
Up-regulation of lysyl oxidase in spontaneous revertants of H-ras-transformed rat fibroblasts.
Alex Hajnal
,
Roman Klemenz
,
Reinhold Schäfer
Cancer Research
1993
Corpus ID: 10712543
Neoplastic transformation mediated by ras oncogenes is associated with down-regulation of gene expression. We have constructed a…
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Highly Cited
1990
Highly Cited
1990
Cloning of rat aorta lysyl oxidase cDNA: complete codons and predicted amino acid sequence.
P. Trackman
,
A. M. Pratt
,
+4 authors
H. Kagan
Biochemistry
1990
Corpus ID: 12928013
Lysyl oxidase cDNA clones were identified by their reactivity with anti-bovine lysyl oxidase in a neonatal rat aorta cDNA lambda…
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Highly Cited
1979
Highly Cited
1979
Purification and properties of four species of lysyl oxidase from bovine aorta.
H. Kagan
,
K. Sullivan
,
T. Olsson
,
A. Cronlund
Biochemical Journal
1979
Corpus ID: 23980209
Lysyl oxidase of bovine aorta was resolved into four enzymically active species by elution from DEAE-cellulose with a salt…
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Highly Cited
1974
Highly Cited
1974
Catalytic activity of aortic lysyl oxidase in an insoluble enzyme-substrate complex.
H. Kagan
,
N. Hewitt
,
L. Salcedo
,
C. Franzblau
Biochimica et Biophysica Acta
1974
Corpus ID: 39662217
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