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LMO1 protein, human
Known as:
LMO1
, Cysteine-Rich Protein TTG-1
, LIM domain only 1 (rhombotin 1) protein, human
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Rhombotin-1 (156 aa, ~18 kDa) is encoded by the human LMO1 gene. This protein is involved in transcriptional regulation.
Topic mentions per year
Topic mentions per year
1995-2017
0
5
10
1995
2017
Related topics
Related topics
11 relations
Cell Proliferation
DNA-Binding Proteins
Genes, Regulator
Homo sapiens
(More)
Broader (2)
LIM Domain Proteins
TRANSCRIPTION FACTOR
Related mentions per year
Related mentions per year
1937-2018
1940
1960
1980
2000
2020
LMO1 protein, human
TRANSCRIPTION FACTOR
Cell Proliferation
dna binding
Homo sapiens
Genes, Regulator
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.
Derek A Oldridge
,
Andrew C. Wood
,
+25 authors
John M. Maris
Nature
2015
Neuroblastoma is a paediatric malignancy that typically arises in early childhood, and is derived from the developing sympathetic…Â
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2014
2014
SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells
Bastien Gerby
,
Cédric S Tremblay
,
+8 authors
Trang Hoang
PLoS genetics
2014
The molecular determinants that render specific populations of normal cells susceptible to oncogenic reprogramming into self…Â
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Highly Cited
2011
Highly Cited
2011
Integrative genomics identifies LMO1 as a neuroblastoma oncogene.
Kai Wang
,
Sharon J. Diskin
,
+30 authors
John M. Maris
Nature
2011
Neuroblastoma is a childhood cancer of the sympathetic nervous system that accounts for approximately 10% of all paediatric…Â
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2010
2010
Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.
Mathieu Tremblay
,
Cédric S Tremblay
,
+4 authors
Trang Hoang
Genes & development
2010
Deciphering molecular events required for full transformation of normal cells into cancer cells remains a challenge. In T-cell…Â
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2004
2004
Null mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in mice.
E. Tse
,
Alan Jay Smith
,
+9 authors
Terence H. Rabbitts
Molecular and cellular biology
2004
The LIM-only family of proteins comprises four members; two of these (LMO1 and LMO2) are involved in human T-cell leukemia via…Â
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Highly Cited
2000
Highly Cited
2000
SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-Tα chain expression
Sabine Herblot
,
Ann-Muriel Steff
,
Patrice Hugo
,
Peter D Aplan
,
Trang Hoang
Nature Immunology
2000
Cooperation between the stem cell leukemia (SCL) transcription factor and its nuclear partners LMO1 or LMO2 induces aggressive T…Â
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1999
1999
Disordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: parallels with E2A-deficient mice.
David S. Chervinsky
,
X. F. Zhao
,
Du H. Lam
,
Marisa A Ellsworth
,
Kevin Gross
,
Peter D Aplan
Molecular and cellular biology
1999
The gene most commonly activated by chromosomal rearrangements in patients with T-cell acute lymphoblastic leukemia (T-ALL) is…Â
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1998
1998
Identification and characterization of LMO4, an LMO gene with a novel pattern of expression during embryogenesis.
D. A. Kenny
,
Linda W. Jurata
,
Yumiko Saga
,
G N Gill
Proceedings of the National Academy of Sciences…
1998
LMO4 is a novel member of the LIM-only (LMO) subfamily of LIM domain-containing transcription factors. LMO1, LMO2, and LMO4 have…Â
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1998
1998
The LMO1 and LDB1 proteins interact in human T cell acute leukaemia with the chromosomal translocation t(11;14)(p15;q11)
Viia E. Valge-Archer
,
Anthony C Forster
,
Terence H. Rabbitts
Oncogene
1998
The ectopic expression of LMO1 or LMO2 in T cell acute leukaemias resulting from chromosomal translocations t(11;14)(p15;q11) or…Â
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Highly Cited
1997
Highly Cited
1997
An scl gene product lacking the transactivation domain induces bony abnormalities and cooperates with LMO1 to generate T-cell malignancies in transgenic mice.
Peter D Aplan
,
C A Jones
,
+5 authors
Kevin Gross
The EMBO journal
1997
The product of the scl (also called tal-1 or TCL5) gene is a basic domain, helix-loop-helix (bHLH) transcription factor required…Â
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