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LIMS1 wt Allele

Known as: PINCH1, PINCH-1, PINCH 
Human LIMS1 wild-type allele is located within 2q12.3-q13 and is approximately 150 kb in length. This allele, which encodes LIM and senescent cell… Expand
National Institutes of Health

Related topics

Related topics

5 relations
2q12.2Homo sapiensSignal Transductionprotein protein interaction

Broader (1)

LIMS1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Rsu1 contributes to regulation of cell adhesion and spreading by PINCH1-dependent and - independent mechanisms
Cell adhesion and migration are complex processes that require integrin activation, the formation and dissolution of focal… Expand
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2011
2011
PINCH1 Is Transcriptional Regulator in Podocytes That Interacts with WT1 and Represses Podocalyxin Expression
Background PINCH1, an adaptor protein containing five LIM domains, plays an important role in regulating the integrin-mediated… Expand
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Highly Cited
2008
Highly Cited
2008
PINCH-1 Regulates the ERK-Bim Pathway and Contributes to Apoptosis Resistance in Cancer Cells*
Resistance to apoptosis is a hallmark of cancer cells. We report here that PINCH-1, a cytoplasmic component of cell-extracellular… Expand
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2007
2007
Pinch1 is required for normal development of cranial and cardiac neural crest-derived structures.
Pinch1, an adaptor protein composed of 5 LIM domains, has been suggested to play an important role in multiple cellular processes… Expand
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2007
2007
Mechanical Stretch Inhibits Oxidized Low Density Lipoprotein-induced Apoptosis in Vascular Smooth Muscle Cells by Up-regulating Integrin αVβ3 and Stablization of PINCH-1*
To determine the mechanisms involved in regulating the balance between apoptosis and survival in vascular smooth muscle cells… Expand
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2006
2006
Warrior Ascetics and Indian Empires
1. Mughal Yogis 2. WarLords 3. Company Gosains 4. Begams and Ranis in Rasdhan 5. Sakti Bhakti 6. Indian Sadhus Kailash's… Expand
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Highly Cited
2005
Highly Cited
2005
PINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytes.
PINCH1, an adaptor protein composed of five LIM domains, mediates protein-protein interactions and functions as a component of… Expand
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2004
2004
Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins and beta-parvins, in regulation of cell morphology and survival.
Proteins at cell-extracellular matrix adhesions (e.g. focal adhesions) are crucially involved in regulation of cell morphology… Expand
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Highly Cited
2003
Highly Cited
2003
PINCH-1 Is an Obligate Partner of Integrin-linked Kinase (ILK) Functioning in Cell Shape Modulation, Motility, and Survival*
PINCH-1 is a widely expressed focal adhesion protein that forms a ternary complex with integrin-linked kinase (ILK) and CH-ILKBP… Expand
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2003
2003
PINCH2 is a new five LIM domain protein, homologous to PINCHand localized to focal adhesions.
PINCH is a five LIM domain protein involved in the regulation of integrin-mediated cell adhesion. It has been shown that PINCH… Expand
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