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LIM Domain

Known as: CRR Domain, Cysteine Rich Region 
The LIM domain is a zinc binding, cysteine rich motif consisting of two tandemly repeated zinc fingers. Unlike GATA type zinc fingers, LIM domains do… 
National Institutes of Health

Related topics

Related topics

19 relations
AJUBA protein, humanCRIP2 protein, humanFHL2 protein, humanLHX1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Analysis of Familial Hemophagocytic Lymphohistiocytosis Type 4 (FHL-4) Mutant Proteins Reveals that S-Acylation Is Required for the Function of Syntaxin 11 in Natural Killer Cells
Natural killer (NK) cell secretory lysosome exocytosis and cytotoxicity are impaired in familial hemophagocytic… 
2013
2013
The upstream sequence segment of the C-terminal cysteine-rich domain is required for microneme trafficking of Plasmodium falciparum erythrocyte binding antigen 175.
2006
2006
Essential role of the LIM domain in the formation of the PKCepsilon-ENH-N-type Ca2+ channel complex.
A LIM domain is a specialized double-zinc finger motif found in a variety of proteins. LIM domains are thought to function as… 
Highly Cited
2000
Highly Cited
2000
The zyxin-related protein TRIP6 interacts with PDZ motifs in the adaptor protein RIL and the protein tyrosine phosphatase PTP-BL.
The small adaptor protein RIL consists of two segments, the C-terminal LIM and the N-terminal PDZ domain, which mediate multiple… 
1999
1999
Mutational analysis and NMR spectroscopy of quail cysteine and glycine-rich protein CRP2 reveal an intrinsic segmental flexibility of LIM domains.
The LIM domain is a conserved cysteine and histidine-containing structural module of two tandemly arranged zinc fingers. It has… 
Highly Cited
1998
Highly Cited
1998
Serine and threonine phosphorylation of the paxillin LIM domains regulates paxillin focal adhesion localization and cell adhesion to fibronectin.
We have previously shown that the LIM domains of paxillin operate as the focal adhesion (FA)-targeting motif of this protein. In… 
1998
1998
Molecular Analysis of the Gal/GalNAc Adhesin of Entamoeba histolytica 1
Attachment of Entamoeba histolytica to colonic epithelium and a variety of other target cells is mediated by a galactosc/N‐acetyl… 
1995
1995
Ligand binding domain of the human endothelin-B subtype receptor.
We have employed both protein chemical and molecular biological approaches to determine the ligand binding domain of the… 
1990
1990
Complete assignment of the 1H NMR spectrum and secondary structure of the DNA binding domain of GAL4
1987
1987
A model for mucus glycoprotein structure.
An approximately 500,000Da subunit characterizes the structural glycoprotein of mucus. This unit is composed of a rod-like very… 
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