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LHX4 gene

Known as: LIM HOMEOBOX GENE 4, LIM Homeobox 4 Gene, LHX4 
This gene plays a role in both transcription and pituitary differentiation.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Context LHX4 encodes a LIM-homeodomain transcription factor that is implicated in early pituitary development. In humans, only 13… 
Review
2011
Review
2011
Highly Cited
2010
Highly Cited
2010
CONTEXT Mutations of multiple transcription factor genes involved in pituitary development have been identified in a minor… 
2009
2009
Heterozygous mutations in LHX4 are associated with combined pituitary hormone deficiency. In this study, the polymorphism of LHX4… 
Highly Cited
2008
Highly Cited
2008
CONTEXT LHX4 is a LIM homeodomain transcription factor involved in pituitary ontogenesis. Only a few heterozygous LHX4 mutations… 
2007
2007
Objective  LHX4 and HESX1 are important in early stages of pituitary development and their mutations can be associated with an… 
Highly Cited
2005
Highly Cited
2005
CONTEXT Pituitary development depends on the actions of a large number of transcription factors. Among them, LHX4 is believed to… 
Highly Cited
2001
Highly Cited
2001
Studies of genetically engineered flies and mice have revealed the role that orthologs of the human LIM homeobox LHX4 have in the… 
Highly Cited
1997
Highly Cited
1997
Lhx3 and Lhx4 (Gsh4), two closely related LIM homeobox genes, determine formation of the pituitary gland in mice. Rathke's pouch… 
1997
1997
LIM homeobox genes are well conserved in evolution and play important roles as transcriptional regulators of embryonic…