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LG100754

 
National Institutes of Health

Papers overview

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2019
2019
The three subtypes (α, β, and γ) of the retinoic acid receptor (RAR) are ligand-dependent transcription factors that mediate… Expand
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2016
2016
Age-related macular degeneration (AMD) is among the main pathologies leading to blindness in adults and has currently no cure or… Expand
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2010
2010
Retinoic acid receptors (RARs) and Retinoid X nuclear receptors (RXRs) are ligand-dependent transcriptional modulators that… Expand
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2007
2007
It is hypothesized that different ligand-induced conformational changes can explain the different interactions of nuclear… Expand
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2002
2002
Insulin resistance and non-insulin-dependent diabetes mellitus are major causes of morbidity and mortality in industrialized… Expand
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2002
2002
9-cis Retinoic acid (RA) induces gene expression in neuroblastoma cells more effectively and with different kinetics than other… Expand
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2001
2001
The RXR serves as a heterodimer partner for the PPARgamma and the dimer is a molecular target for insulin sensitizers such as the… Expand
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Highly Cited
2000
Highly Cited
2000
Hyperlipidemia may complicate the use of HIV protease inhibitors (PIs) in AIDS therapy. To determine the cause of hyperlipidemia… Expand
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1999
1999
Several dibenzodiazepine derivatives were identified as novel retinoid X receptor (RXR) antagonists on the basis of inhibitory… Expand
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Highly Cited
1997
Highly Cited
1997
Regulation of gene expression via allosteric control of transcription is one of the fundamental concepts of molecular biology… Expand
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