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LG 100268
Known as:
LG-100268
, LG100268
Â
Â
National Institutes of Health
Topic mentions per year
Topic mentions per year
1995-2016
0
2
4
6
1995
2016
Related topics
Related topics
2 relations
Broader (2)
Nicotinic Acids
Tetrahydronaphthalenes
Related mentions per year
Related mentions per year
1938-2018
1940
1960
1980
2000
2020
LG 100268
Nicotinic Acids
Tetrahydronaphthalenes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
The Rexinoid LG100268 prevents the development of preinvasive and invasive estrogen receptor negative tumors in MMTV-erbB2 mice.
Yuxin Li
,
Yun Zhang
,
+7 authors
Powel H. Brown
Clinical cancer research : an official journal of…
2007
PURPOSE To test whether a novel rexinoid, LG100268, prevents the development of preinvasive and invasive estrogen receptor…Â
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2002
2002
Prevention and treatment of experimental breast cancer with the combination of a new selective estrogen receptor modulator, arzoxifene, and a new rexinoid, LG 100268.
Nanjoo Suh
,
William W. Lamph
,
+7 authors
Michael B. Sporn
Clinical cancer research : an official journal of…
2002
The selective estrogen receptor modulator arzoxifene and the rexinoid LG 100268 were active not only as single agents for…Â
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Highly Cited
2002
Highly Cited
2002
Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia.
Marina Konopleva
,
Twee Y Tsao
,
+14 authors
Michael Andreeff
Blood
2002
It has been shown that the novel synthetic triterpenoid CDDO inhibits proliferation and induces differentiation and apoptosis in…Â
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2002
2002
The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12.
James D. Love
,
John T Gooch
,
+5 authors
John W R Schwabe
The Journal of biological chemistry
2002
Ligands that specifically target retinoid-X receptors (RXRs) are emerging as potentially powerful therapies for cancer, diabetes…Â
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2000
2000
Insulin sensitizer, troglitazone, directly inhibits aromatase activity in human ovarian granulosa cells.
Yulan Mu
,
T. Yanase
,
+5 authors
Hiroshi Nawata
Biochemical and biophysical research…
2000
Ovarian granulosa cells synthesize estrogens from androgens, which are catalyzed by aromatase cytochrome P450 (P450arom…Â
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2000
2000
HIV protease inhibitors stimulate hepatic triglyceride synthesis.
J. M. Lenhard
,
Dallas K Croom
,
J. E. Weiel
,
Deborah A. Winegar
Arteriosclerosis, thrombosis, and vascular…
2000
Hyperlipidemia may complicate the use of HIV protease inhibitors (PIs) in AIDS therapy. To determine the cause of hyperlipidemia…Â
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Highly Cited
1999
Highly Cited
1999
Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in human transitional bladder cancer and its role in inducing cell death.
Y. F. Guan
,
Y. H. Zhang
,
Robert Breyer
,
Leigh Davis
,
M. D. Breyer
Neoplasia
1999
The present study examined the expression and role of the thiazolidinedione (TZD)-activated transcription factor, peroxisome…Â
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1999
1999
The RXR agonist LG100268 causes hepatomegaly, improves glycaemic control and decreases cardiovascular risk and cachexia in diabetic mice suffering from pancreatic beta-cell dysfunction
J. M. Lenhard
,
Mary E. Lancaster
,
+6 authors
Harrison Brown
Diabetologia
1999
Aims/hypothesis. Although retinoid X receptor (RXR) and peroxisome proliferator activated receptor-γ (PPARγ) agonists have…Â
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Highly Cited
1995
Highly Cited
1995
Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells.
Markus Böhm
,
L Zhang
,
+7 authors
Richard A. Heyman
Journal of medicinal chemistry
1995
Structural modifications of the retinoid X receptor (RXR) selective compound 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2…Â
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1995
1995
9-cis retinoic acid inhibition of activation-induced apoptosis is mediated via regulation of fas ligand and requires retinoic acid receptor and retinoid X receptor activation.
R Bissonnette
,
Timothy A. Brunner
,
+4 authors
Richard A. Heyman
Molecular and cellular biology
1995
T-cell hybridomas, thymocytes, and T cells can be induced to undergo apoptotic cell death by activation through the T-cell…Â
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