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LG 100268

Known as: LG-100268, LG100268 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Nicotinic AcidsTetrahydronaphthalenes

Papers overview

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2019
2019
Testing Novel Pyrimidinyl Rexinoids: A New Paradigm for Evaluating Rexinoids for Cancer Prevention
Rexinoids, selective ligands for retinoid X receptors (RXR), have shown promise in preventing many types of cancer. However, the… 
2008
2008
Development and quality of bovine morulae cultured in serum-free medium with specific retinoid receptor agonists.
Retinoids regulate development and differentiation of the bovine blastocyst in vitro, although the underlying mechanisms remain… 
2007
2007
Screening for ligands of human retinoid X receptor-alpha using ultrafiltration mass spectrometry.
Retinoid X receptors (RXRs) function as ligand-activated transcription factors and are obligatory components of a large number of… 
Highly Cited
2005
Highly Cited
2005
2-Cyano-3,12-dioxoolean-1,9-dien-28-oic Acid and Related Compounds Inhibit Growth of Colon Cancer Cells through Peroxisome Proliferator-Activated Receptor γ-Dependent and -Independent Pathways
2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO) and the corresponding methyl (CDDO-Me) and imidazole (CDDO-Im) esters induce… 
2005
2005
Thiazolidinediones inhibit proliferation of microvascular and macrovascular cells by a PPARγ-independent mechanism
Aims/hypothesisThis study evaluated the hypothesis that peroxisome proliferator-activated receptor-γ (PPARγ) agonists, including… 
2004
2004
Capsaicin inhibits the production of tumor necrosis factor alpha by LPS-stimulated murine macrophages, RAW 264.7: a PPARgamma ligand-like action as a novel mechanism.
Capsaicin, a major ingredient of hot pepper, is considered to exhibit anti-inflammatory properties. Our previous study… 
2000
2000
A nuclear receptor system constituted by RAR and RXR induces aromatase activity in MCF-7 human breast cancer cells
1999
1999
The expression and activity of D-type cyclins in F9 embryonal carcinoma cells: modulation of growth by RXR-selective retinoids.
The growth rate of malignant F9 embryonal carcinoma cells slows considerably following all-trans-retinoic acid-induced… 
Highly Cited
1998
Highly Cited
1998
Effects of retinoid treatment of rats on hepatic microsomal metabolism and cytochromes P450. Correlation between retinoic acid receptor/retinoid x receptor selectivity and effects on metabolic…
Retinoids are compounds that bind to and activate one or more retinoid receptors to elicit various physiological responses. There… 
Highly Cited
1997
Highly Cited
1997
Retinoid X Receptor (RXR) Ligands Activate the Human 25-Hydroxyvitamin D3-24-hydroxylase Promoter via RXR Heterodimer Binding to Two Vitamin D-responsive Elements and Elicit Additive Effects with 1…
We have previously shown that RNA levels of kidney 25-hydroxyvitamin D3-24-hydroxylase (24(OH)ase), a key metabolic enzyme for 1… 
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