Skip to search formSkip to main contentSkip to account menu

LErafAON

Known as: liposome-encapsulated c-raf antisense oligodeoxynucleotide, c-raf antisense oligonucleotide liposome, c-raf Antisense Oligodeoxynucleotide Liposome 
The liposomal formulation of a c-raf-1 antisense oligonucleotide, with potential antineoplastic activity. Liposomal c-raf antisense oligonucleotide… 
National Institutes of Health

Related topics

Related topics

2 relations
NCIt Antineoplastic Agent Terminology

Broader (1)

Oligodeoxyribonucleotides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Inhibition of LNCaP prostate cancer cells by means of androgen receptor antisense oligonucleotides
Currently available methods for treatment of human prostatic carcinoma aim to inactivate the androgen receptor (AR) by androgen… 
Highly Cited
2000
Highly Cited
2000
Eradication of human non-Hodgkin's lymphoma in SCID mice by BCL-2 antisense oligonucleotides combined with low-dose cyclophosphamide.
Cancers overexpressing Bcl-2 protein, which prevents programmed cell death (apoptosis), are less sensitive to stresses that… 
Highly Cited
2000
Highly Cited
2000
Antisense oligonucleotides against protein kinase CK2‐α inhibit growth of squamous cell carcinoma of the head and neck in vitro
Human squamous cell carcinomas of the head and neck (SCCHN) overexpress the protein kinase CK2, and elevated CK2 activity… 
Highly Cited
2000
Highly Cited
2000
Molecular and pharmacokinetic properties associated with the therapeutics of bcl-2 antisense oligonucleotide G3139 combined with free and liposomal doxorubicin.
Bcl-2 is a key apoptosis-regulating protein that has been implicated in mechanisms of chemoresistance for a variety of… 
Highly Cited
2000
Highly Cited
2000
Involvement of the Ets-1 gene in overexpression of matrilysin in human hepatocellular carcinoma.
Although matrix metalloproteinases (MMPs) are thought to be involved in the invasion and metastasis of a variety of malignant… 
Review
1999
Review
1999
Antisense oligonucleotides as therapeutic agents
Antisense oligonucleotides can block the expression of specific target genes involved in the development of human diseases… 
Highly Cited
1997
Highly Cited
1997
Combinatorial Screening and Rational Optimization for Hybridization to Folded Hepatitis C Virus RNA of Oligonucleotides with Biological Antisense Activity*
We describe our initial application of a biochemical strategy, comprising combinatorial screening and rational optimization… 
Review
1997
Review
1997
Antisense oligonucleotides as therapeutics for malignant diseases.
The continued progress in our understanding of the biology of neoplasia and in the identification, cloning, and sequencing of… 
Highly Cited
1996
Highly Cited
1996
Antisense oligonucleotides specific for transforming growth factor beta2 inhibit the growth of malignant mesothelioma both in vitro and in vivo.
Highly Cited
1992
Highly Cited
1992
B-myb antisense oligonucleotides inhibit proliferation of human hematopoietic cell lines.
The B-myb gene is highly homologous to the c-myb protooncogene in several domains and also shares some of the functions of c-myb… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)