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LErafAON
Known as:
liposome-encapsulated c-raf antisense oligodeoxynucleotide
, c-raf antisense oligonucleotide liposome
, c-raf Antisense Oligodeoxynucleotide Liposome
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The liposomal formulation of a c-raf-1 antisense oligonucleotide, with potential antineoplastic activity. Liposomal c-raf antisense oligonucleotide…
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National Institutes of Health
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Related topics
Related topics
2 relations
NCIt Antineoplastic Agent Terminology
Broader (1)
Oligodeoxyribonucleotides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Therapeutic Targeting of Interferon Regulatory Factor 4 with Next Generation Antisense Oligonucleotides Produces Robust In Vivo Antitumor Activity in Preclinical Models of Multiple Myeloma
Tianyuan Zhou
,
Joanna Schmidt
,
Youngsoo Kim
,
A. Macleod
2017
Corpus ID: 203832101
Despite significant recent advances in therapeutic options, multiple myeloma (MM) remains an incurable disease, and novel agents…
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2016
2016
Suppression of Bcl-2 by Antisense Oligonucleotides is Compensated through Increased Activity of the Androgen Receptor and Co-Activators but not 5-alpha Reductase
M. Rubenstein
2016
Corpus ID: 212448587
Antisense oligonucleotides (oligos) have targeted regulatory proteins in both in vivo and in vitro prostate cancer models. In…
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Review
2013
Review
2013
Antisense Oligonucleotides Therapy in the Treatment of Cerebral Gliomas: A Review
M. Caffo
,
G. Caruso
,
M. Passalacqua
,
F. Angileri
,
F. Tomasello
2013
Corpus ID: 17447294
Patients affected by cerebral gliomas, despite classical strategies adopted, show a very poor prognosis. Current treatment…
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2013
2013
Antisense Oligonucleotides Therapy: A New Potential Tool in the Treatment of Cerebral Gliomas
G. Caruso
,
M. Caffo
,
M. Pino
,
G. Raudino
2013
Corpus ID: 83619255
2010
2010
Phase I portion of the phase I-II study of the X-linked inhibitor of apoptosis (XIAP) antisense AEG35156 in combination with sorafenib in patients with advanced hepatocellular carcinoma (HCC).
A. Lee
,
B. Zee
,
+5 authors
S.-Y. Tung
2010
Corpus ID: 79430722
e14519 Background: The X-linked Inhibitor of Apoptosis (XIAP) inhibits caspases 3, 7 and 9 which are proteases responsible for…
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2004
2004
Strategies for Inhibition of MDR 1 Gene Expression
Dong Xu
,
Hyunmin Kang
,
M. Fisher
,
R. Juliano
2004
Corpus ID: 7423344
Several distinct strategies have been used to modulate the expression of cancer-associated genes, including antisense…
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2004
2004
Inhibition of TF gene expression by antisense oligonucleotides in different cancer cell lines.
Y. Förster
,
B. Schwenzer
Journal of experimental therapeutics and oncology
2004
Corpus ID: 46659100
Human tissue factor (TF) is the initiator of blood coagulation. Beside this function it is involved in tumor angiogenesis and…
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Review
2002
Review
2002
Minireview Antisense Oligonucleotides : Basic Concepts and Mechanisms
N. Dias
,
C. Stein
2002
Corpus ID: 35574392
Conceptual simplicity, the possibility of rational design, relatively inexpensive cost, and developments in the sequencing of…
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2001
2001
p 53-independent Induction of Apoptosis in Human Melanoma Cells by a bcl-2 / bcl-xL Bispecific Antisense Oligonucleotide 1
M. Rieber
,
U. Zangemeister-Wittke
,
M. Rieber
2001
Corpus ID: 27618481
Mutations in the p53 tumor suppressor gene are implicated in defective apoptotic response of tumors to genotoxic damage and, thus…
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Review
2000
Review
2000
Antisense oligonucleotides as anti-tumor therapeutics
Rui-Wen Zhang
,
Hui Wang
2000
Corpus ID: 88916115
Since the concept of antisense therapy was introduced over 20 years ago, antisense oligonucleotides have been shown to be unique…
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