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LE 135

Known as: LE-135, LE135 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
The accumulation of plaques of β‐amyloid (Aβ) peptides, a hallmark of Alzheimer's disease, results from the sequential cleavage… 
Highly Cited
2014
2011
2011
Retinoic acid receptor beta 2 (RARβ2) has been proposed as an important receptor mediating retinoid‐induced axonal growth and… 
Highly Cited
2009
Highly Cited
2009
IBD is characterized by uncontrolled immune responses in inflamed mucosa, with dominance of IL‐17‐producing cells and deficiency… 
Highly Cited
2003
Highly Cited
2003
The vitamin A metabolite, retinoic acid (RA), affects Th1 and Th2 development. The effect is partly exerted through the… 
Review
2002
Review
2002
  • H. Kagechika
  • Current medicinal chemistry
  • 2002
  • Corpus ID: 43779621
Retinoids, all-trans-retinoic acid (1a) and its analogs, act as specific modulators of cellular differentiation and proliferation… 
Highly Cited
1999
Highly Cited
1999
Four candidate retinoid antagonists (LE135, LE511, LE540, and LE550) were designed on the basis of the ligand superfamily concept… 
Highly Cited
1997
Highly Cited
1997
In human HL-60 promyelocytic leukemia cells, diazepinylbenzoic acid derivatives can exhibit either antagonistic or synergistic…