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LE 135
Known as:
LE-135
, LE135
Â
Â
National Institutes of Health
Topic mentions per year
Topic mentions per year
1996-2015
0
2
4
1996
2015
Related topics
Related topics
1 relation
Broader (1)
Dibenzazepines
Related mentions per year
Related mentions per year
1969-2018
1960
1980
2000
2020
LE 135
Dibenzazepines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Cilostazol suppresses β-amyloid production by activating a disintegrin and metalloproteinase 10 via the upregulation of SIRT1-coupled retinoic acid receptor-β.
Hye Rin Lee
,
Hwa Kyoung Shin
,
+5 authors
Chi Dae Kim
Journal of neuroscience research
2014
The accumulation of plaques of β-amyloid (Aβ) peptides, a hallmark of Alzheimer's disease, results from the sequential cleavage…Â
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2014
2014
Regulating chondrogenesis of human mesenchymal stromal cells with a retinoic Acid receptor-Beta inhibitor: differential sensitivity of chondral versus osteochondral development.
Solvig Diederichs
,
Kerstin Zachert
,
Patric Raiss
,
Wiltrud Richter
Cellular physiology and biochemistry…
2014
AIM Main objective was to investigate whether the synthetic retinoic acid receptor (RAR)-β antagonist LE135 is able to drive in…Â
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2014
2014
All-trans retinoic acid attenuates experimental colitis through inhibition of NF-κB signaling.
Kai Hong
,
Yi Zhang
,
+5 authors
Aiping Bai
Immunology letters
2014
Inflammatory bowel disease (IBD) is characterized by excessive innate immune cell activation, which is responsible for tissue…Â
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2013
2013
Retinoic acid receptor beta mediates all-trans retinoic acid facilitation of mesenchymal stem cells neuronal differentiation.
Min Gong
,
Yang Bi
,
+5 authors
Tingyu Li
The international journal of biochemistry & cell…
2013
All-trans retinoic acid plays an important role in nervous system development. However, the effects of all-trans retinoic acid on…Â
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2010
2010
All-trans retinoic acid ameliorates trinitrobenzene sulfonic acid-induced colitis by shifting Th1 to Th2 profile.
Aiping Bai
,
Nong-Hua Lu
,
+6 authors
Yuan Guo
Journal of interferon & cytokine research : the…
2010
Inflammatory bowel disease is characterized with uncontrolled immune response in inflamed mucosa, with dominance of Th1 cells…Â
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2005
2005
Retinoic acid-dependent attraction of adult spinal cord axons towards regenerating newt limb blastemas in vitro.
Jennifer M. Dmetrichuk
,
Gaynor E. Spencer
,
Robert L. Carlone
Developmental biology
2005
Adult urodele amphibians possess the unique ability to regenerate amputated limbs and to re-innervate these regenerating…Â
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Highly Cited
2004
Highly Cited
2004
Retinoic acid imprints gut-homing specificity on T cells.
Makoto Iwata
,
Asami Hirakiyama
,
Yuko Eshima
,
Hiroyuki Kagechika
,
Chieko Kato
,
Si-Young Song
Immunity
2004
For a preferential homing of T cells to the gut, expression of the integrin alpha4beta7 and the chemokine receptor CCR9 is…Â
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2002
2002
Retinoid antagonists inhibit normal patterning during limb regeneration in the axolotl, Ambystoma mexicanum.
Sonia Victoria del Rincón
,
Steven R Scadding
The Journal of experimental zoology
2002
Retinoic acid (RA) has been detected in the regenerating limb of the axolotl, and exogenous RA can proximalize, posteriorize, and…Â
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1999
1999
Identification of a novel class of retinoic acid receptor beta-selective retinoid antagonists and their inhibitory effects on AP-1 activity and retinoic acid-induced apoptosis in human breast cancer…
Yixun Li
,
Y.. Hashimoto
,
Anissa Agadir
,
Hiroyuki Kagechika
,
X. K. Zhang
The Journal of biological chemistry
1999
Four candidate retinoid antagonists (LE135, LE511, LE540, and LE550) were designed on the basis of the ligand superfamily concept…Â
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1997
1997
Regulation of retinoidal actions by diazepinylbenzoic acids. Retinoid synergists which activate the RXR-RAR heterodimers.
Hiroki Umemiya
,
Hiroshi Fukasawa
,
+7 authors
Hiroyuki Kagechika
Journal of medicinal chemistry
1997
In human HL-60 promyelocytic leukemia cells, diazepinylbenzoic acid derivatives can exhibit either antagonistic or synergistic…Â
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