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LE 135

Known as: LE-135, LE135 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2015
02419962015

Related topics

Related topics

1 relation

Broader (1)

Dibenzazepines

Related mentions per year

Related mentions per year

1969-2018
1960198020002020
LE 135
Dibenzazepines

Papers overview

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2014
2014
Cilostazol suppresses β-amyloid production by activating a disintegrin and metalloproteinase 10 via the upregulation of SIRT1-coupled retinoic acid receptor-β.
The accumulation of plaques of β-amyloid (Aβ) peptides, a hallmark of Alzheimer's disease, results from the sequential cleavage… (More)
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2014
2014
Regulating chondrogenesis of human mesenchymal stromal cells with a retinoic Acid receptor-Beta inhibitor: differential sensitivity of chondral versus osteochondral development.
AIM Main objective was to investigate whether the synthetic retinoic acid receptor (RAR)-β antagonist LE135 is able to drive in… (More)
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2014
2014
All-trans retinoic acid attenuates experimental colitis through inhibition of NF-κB signaling.
Inflammatory bowel disease (IBD) is characterized by excessive innate immune cell activation, which is responsible for tissue… (More)
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2013
2013
Retinoic acid receptor beta mediates all-trans retinoic acid facilitation of mesenchymal stem cells neuronal differentiation.
All-trans retinoic acid plays an important role in nervous system development. However, the effects of all-trans retinoic acid on… (More)
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2010
2010
All-trans retinoic acid ameliorates trinitrobenzene sulfonic acid-induced colitis by shifting Th1 to Th2 profile.
Inflammatory bowel disease is characterized with uncontrolled immune response in inflamed mucosa, with dominance of Th1 cells… (More)
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2005
2005
Retinoic acid-dependent attraction of adult spinal cord axons towards regenerating newt limb blastemas in vitro.
Adult urodele amphibians possess the unique ability to regenerate amputated limbs and to re-innervate these regenerating… (More)
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Highly Cited
2004
Highly Cited
2004
Retinoic acid imprints gut-homing specificity on T cells.
For a preferential homing of T cells to the gut, expression of the integrin alpha4beta7 and the chemokine receptor CCR9 is… (More)
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2002
2002
Retinoid antagonists inhibit normal patterning during limb regeneration in the axolotl, Ambystoma mexicanum.
Retinoic acid (RA) has been detected in the regenerating limb of the axolotl, and exogenous RA can proximalize, posteriorize, and… (More)
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1999
1999
Identification of a novel class of retinoic acid receptor beta-selective retinoid antagonists and their inhibitory effects on AP-1 activity and retinoic acid-induced apoptosis in human breast cancer…
Four candidate retinoid antagonists (LE135, LE511, LE540, and LE550) were designed on the basis of the ligand superfamily concept… (More)
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1997
1997
Regulation of retinoidal actions by diazepinylbenzoic acids. Retinoid synergists which activate the RXR-RAR heterodimers.
In human HL-60 promyelocytic leukemia cells, diazepinylbenzoic acid derivatives can exhibit either antagonistic or synergistic… (More)
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