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LCL161
Known as:
Smac Mimetic LCL161
An orally bioavailable second mitochondrial-derived activator of caspases (SMAC) mimetic and inhibitor of IAP (Inhibitor of Apoptosis Protein) family…
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National Institutes of Health
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Related topics
Related topics
2 relations
NCIt Antineoplastic Agent Terminology
Broader (1)
Thiazoles
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Abstract 3070: Lenalidomide and SMAC mimetic LCL161 show combination activity in cells harboring loss of chromosome 5q
N. Hafeez
,
A. Gaither
,
D. Porter
2017
Corpus ID: 80133129
2016
2016
[Effects of LCL161, a Smac mimetic on the proliferation and apoptosis in hepatocellular carcinoma cells].
K. Ren
,
Lin-Yan Ma
,
+4 authors
Su-Rong Zhao
Zhong nan da xue xue bao. Yi xue ban = Journal of…
2016
Corpus ID: 22543800
OBJECTIVE To investigate the effects of LCL161, a Smac mimetic, on the proliferation and apoptosis in hepatocellular carcinoma…
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2013
2013
Abstract OT1-4-04: A phase II randomized, open-label, neoadjuvant study of LCL161, an oral antagonist of inhibitor of apoptosis proteins, in combination with paclitaxel in patients with triple…
A. Lluch-Hernández
,
A. R. Simón
,
+16 authors
A. Bardia
2013
Corpus ID: 71394353
Background: Inhibitor of apoptosis proteins (IAPs) negatively regulate cell death through a variety of mechanisms. LCL161 is an…
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2013
2013
Eine randomisierte, unverblindete, neoadjuvante Phase-II-Studie mit einer wöchentlichen Gabe von Paclitaxel mit oder ohne LCL161, einem oralen IAP- Antagonisten (inhibitor of proteins, IAP), bei…
C. Liedtke
,
R. Dienstmann
,
+9 authors
J. Infante
2013
Corpus ID: 75284162