LBQ657
National Institutes of Health
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Neprilysin, also known as neutral endopeptidase, is a cell surface membrane metalo-endopeptidase that cleaves various peptides…
Simultaneous inhibition of neprilysin and angiotensin II receptors by sacubitril/valsartan was shown to significantly…
Objective
To explore the effect and mechanism of Sacubitril/Valsartan on myocardial remodeling and cardiac function in rats with…
We thank Rajapakse et al for expanding on our point about the role of neprilysin in amyloid-β degradation from our review article…
1115 Abstract—Heart failure affects ≈5.7 million people in the United States alone. Angiotensin-converting enzyme inhibitors…
LCZ696 (sacubitril/valsartan), a novel angiotensin receptor neprilysin inhibitor has been recently approved for the treatment of…
LCZ696 (sacubitril/valsartan), an angiotensin receptor neprilysin inhibitor, is indicated for chronic heart failure (HF) and…