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LBQ657

National Institutes of Health

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2 relations

Broader (2)

AminobutyratesBiphenyl Compounds

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Radiosynthesis of the 11 C-methyl derivative of LBQ657 for PET investigation of the neprilysin inhibitor sacubitril.
Neprilysin, also known as neutral endopeptidase, is a cell surface membrane metalo-endopeptidase that cleaves various peptides… 
2019
2019
P3829Antiarrhythmic effects of Sacubitrilat (LBQ657) on Ca2+ homeostasis in ventricular cardiomyocytes
Simultaneous inhibition of neprilysin and angiotensin II receptors by sacubitril/valsartan was shown to significantly… 
2019
2019
Effects of Sacubitril/Valsartan on myocardial remodeling and cardiac function in rats with myocardial infarction
Objective To explore the effect and mechanism of Sacubitril/Valsartan on myocardial remodeling and cardiac function in rats with… 
2016
2016
Assessment of Drug–Drug Interaction Potential Between Atorvastatin and LCZ696, A Novel Angiotensin Receptor Neprilysin Inhibitor, in Healthy Chinese Male Subjects
LCZ696 (sacubitril/valsartan), a novel angiotensin receptor neprilysin inhibitor has been recently approved for the treatment of… 
Review
2016
Review
2016
March 15 , 2016 by blocking vascular and adrenal
1115 Abstract—Heart failure affects ≈5.7 million people in the United States alone. Angiotensin-converting enzyme inhibitors… 
2016
2016
Effect of renal function on the pharmacokinetics of LCZ696 (sacubitril/valsartan), an angiotensin receptor neprilysin inhibitor
LCZ696 (sacubitril/valsartan), an angiotensin receptor neprilysin inhibitor, is indicated for chronic heart failure (HF) and… 
2015
2015
LCZ696 (sacubitril/valsartan), an angiotensin receptor neprilysin inhibitor (ARNI): clinical development in heart failure
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