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LB42908

Known as: LB 42908 
 
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Farnesyltransferase inhibitors (FTIs) have mainly been used in cancer therapy. However, more recently, investigations on these… Expand
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2012
2012
Metabolism of LB42908, a novel farnesyl transferase inhibitor, was investigated for preclinical development. In vitro hepatic… Expand
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2006
2006
LB42708 (LB7) and LB42908 (LB9) are pyrrole-based orally active farnesyltransferase inhibitors (FTIs) that have similar… Expand
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2006
2006
As farnesylation of the Ras protein by farnesyl transferase is a critical step for the Ras functional activity, the farnesyl… Expand
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2005
2005
Interleukin-12 (IL-12) gene was shown to produce both IL-12 and p40 subunit. The excess production of the p40 subunit as a… Expand
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2001
2001
Design, synthesis and structure-activity relationship of a class of aryl pyrroles as farnesyltransferase inhibitors are described… Expand
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