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LB 30870

Known as: LB-30870, LB30870 
National Institutes of Health

Papers overview

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2016
2016
A Food Effect Study of an Oral Thrombin Inhibitor and Prodrug Approach To Mitigate It.
LB30870, a new direct thrombin inhibitor, showed 80% reduction in oral bioavailability in fed state. The present study aims to… 
2015
2015
Pharmacokinetics, pharmacodynamics and food effect of LB30870, a novel direct thrombin inhibitor, after single oral doses in healthy men
Abstract 1. The safety, tolerability, pharmacokinetics, pharmacodynamics, and food effect of LB30870, a new selective thrombin… 
2013
2013
Pharmacokinetics and dose-dependency of LB30870 in rats, dogs, and monkeys
This study was to examine the pharmacokinetics of LB30870, a thrombin inhibitor, after IV and oral administration to rats, dogs… 
2001
2001
In vitro characteristics and antithrombotic effects of LB30870, a potent, orally active and selective direct thrombin inhibitor, in rat model of venous thrombosis
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