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LARP6 gene

Known as: La ribonucleoprotein domain family member 6, LARP6, ACHERON 
 
National Institutes of Health

Papers overview

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2015
2015
Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module
The La-related proteins (LARPs) form a diverse group of RNA-binding proteins characterized by the possession of a composite RNA… Expand
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2014
2014
Insulin-like Growth Factor-1 Increases Synthesis of Collagen Type I via Induction of the mRNA-binding Protein LARP6 Expression and Binding to the 5′ Stem-loop of COL1a1 and COL1a2 mRNA*
Background: The la ribonucleoprotein domain family member 6, LARP6, regulates collagen type 1 mRNA translation. Results: IGF-1… Expand
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2014
2014
Characterization of binding of LARP6 to the 5’ stem-loop of collagen mRNAs: Implications for synthesis of type I collagen
Type I collagen is composed of 2 polypeptides, α1(I) and α2(I), which fold into triple helix. Collagen α1(I) and α2(I) mRNAs have… Expand
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2012
2012
A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs.
Type I collagen is composed of two α1(I) polypeptides and one α2(I) polypeptide and is the most abundant protein in the human… Expand
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Highly Cited
2011
Highly Cited
2011
A novel role of vimentin filaments: binding and stabilization of collagen mRNAs.
The stem-loop in the 5' untranslated region (UTR) of collagen α1(I) and α2(I) mRNAs (5'SL) is the key element regulating their… Expand
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Highly Cited
2010
Highly Cited
2010
Binding of LARP6 to the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen.
Type I collagen is the most abundant protein in the human body, produced by folding of two alpha1(I) polypeptides and one alpha2… Expand
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Highly Cited
2009
Highly Cited
2009
A comprehensive analysis of the La-motif protein superfamily.
The extremely well-conserved La motif (LAM), in synergy with the immediately following RNA recognition motif (RRM), allows direct… Expand
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2007
2007
Acheron, a novel member of the Lupus Antigen family, is induced during the programmed cell death of skeletal muscles in the moth Manduca sexta.
In order to identify novel genes associated with the initiation of programmed cell death during development, we employed a… Expand
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1995
1995
Cloning and sequencing of a human endothelin converting enzyme in renal adenocarcinoma (ACHN) cells producing endothelin-2.
Endothelin (ET)-2 is a 21 residue vasoactive peptide which is biosynthesized from big ET-2(1-38) by a specific cleavage at Trp21… Expand
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Highly Cited
1986
Highly Cited
1986
GEOLOGIC MAP OF THE WESTERN EQUATORIAL REGION OF MARS
Although the origin and composition of many units are obscure or controversial, their interpretations are based on objective… Expand
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