LAP2alpha
National Institutes of Health
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Mutations in several genes encoding nuclear envelope (NE) associated proteins cause Emery–Dreifuss muscular dystrophy (EDMD). We…
ABSTRACT The human nuclear envelope proteins emerin and lamina-associated polypeptide 2α (LAP2α) have been proposed to aid in the…
The nucleoplasmic protein, Lamina-associated polypeptide (LAP) 2α, is one of six alternatively spliced products of the LAP2gene…
Lamina-associated polypeptides (LAPs) are important components of the nuclear lamina, the dense network of filaments that…
Deregulation of the retinoblastoma (pRB) tumor suppressor pathway is frequently observed in human cancer and associated with…
LAP2α is a LEM family protein associated with nucleoplasmic A-type lamins and chromatin in interphase. Like lamins and other…
The mammalian lamina-associated polypeptide 2 (LAP2) gene encodes six isoforms (LAP2alpha, beta, delta, epsilon, gamma, zeta…
Somatic and germinal cells of 15 fish and 33 amphibian species were examined by SDS-PAGE followed by immunoblotting to determine…