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L796778

Known as: L-796,778 
 
National Institutes of Health

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2 relations

Broader (2)

AmidesNitrobenzenes

Papers overview

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2011
2011
Rat hippocampal somatostatin sst3 and sst4 receptors mediate anticonvulsive effects in vivo: Indications of functional interactions with sst2 receptors
Somatostatin-14 (SRIF) is a potent anticonvulsant in rodent models of limbic seizures in which the hippocampus is its major site… Expand
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Highly Cited
2010
Highly Cited
2010
Somatostatin signaling in neuronal cilia is critical for object recognition memory.
Most neurons possess a single, nonmotile cilium that projects out from the cell surface. These microtubule-based organelles are… Expand
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2008
2008
Activation of somatostatin receptors in the globus pallidus increases rat locomotor activity and dopamine release in the striatum
RationaleSomatostatin and its receptors have been localized in brain nuclei implicated in motor control, such as the striatum… Expand
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2006
2006
Somatostatin receptors (sst2) regulate cGMP production in rat retina
The present study investigated the effect of somatostatin in the regulation of cGMP levels in rat retina and the mechanisms… Expand
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2005
2005
Mechanisms of somatostatin-evoked responses in neurons of the rat lateral amygdala.
The effects of somatostatin in the rat lateral amygdala (LA) in vitro were investigated through whole cell recording techniques… Expand
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2003
2003
Characterisation of [125I]-TyroDTrp8-somatostatin binding in sst1- to sst4- and SRIF-gene-invalidated mouse brain
Five somatostatin receptors (sst) have been cloned and mRNAs for the first four (sst1–4) are expressed in many brain regions. In… Expand
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2002
2002
Somatostatin Receptor Subtypes 2 and 5 Inhibit Corticotropin-Releasing Hormone-Stimulated Adrenocorticotropin Secretion from AtT-20 Cells
Somatostatin (SRIH) regulates pituitary adrenocorticotropin (ACTH) secretion by interacting with a family of homologous G protein… Expand
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2002
2002
Anti-secretory properties of non-peptide somatostatin receptor agonists in isolated rat colon: luminal activity and possible interaction with P-glycoprotein.
1. The diverse physiological actions of somatostatin are mediated by a family of G-protein coupled receptors (SSTRs). Several… Expand
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Highly Cited
2001
Highly Cited
2001
Homo- and heterodimerization of somatostatin receptor subtypes. Inactivation of sst(3) receptor function by heterodimerization with sst(2A).
Several recent studies suggest that G protein-coupled receptors can assemble as heterodimers or hetero-oligomers with enhanced… Expand
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2000
2000
Somatostatin potentiates NMDA receptor function via activation of InsP(3) receptors and PKC leading to removal of the Mg(2+) block without depolarization.
N-methyl-D-aspartate (NMDA) receptors exist on noradrenergic axon terminals and mediate enhancement of noradrenaline (NA) release… Expand
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