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L2HGDH gene

Known as: L-2-HYDROXYGLUTARATE DEHYDROGENASE, C14ORF160, 2-hydroxyglutarate dehydrogenase 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
[A pedigree of L-2-hydroxyglutaric aciduria including 3 patients caused by homozygous L2HGDH variant].
2019
2019
Epigenetic dysregulation by aberrant metabolism in renal cell carcinoma can be reversed with Ascorbic acid
ABSTRACT Our recently published study uncovered mechanisms and prognostic impact of aberrant DNA methylation/hydroxymethylation… 
2018
2018
Retroviral signature can predict therapy outcome
2016
2016
White matter abnormalities in an adult patient with l-2-hydroxyglutaric aciduria
2016
2016
[Analysis of L2HGDH gene mutation in a patient with 2-hydroxyglutaric aciduria].
OBJECTIVE To explore pathogenic mutation in a family affected with 2-hydroxyglutaric aciduria. METHODS Exons of 3 candidate… 
2015
2015
Plants Possess a Cyclic Mitochondrial Metabolic Pathway similar to the Mammalian Metabolic Repair Mechanism Involving Malate Dehydrogenase and l-2-Hydroxyglutarate Dehydrogenase.
Enzymatic side reactions can give rise to the formation of wasteful and toxic products that are removed by metabolite repair… 
2015
2015
Another small molecule in the oncometabolite mix: L-2-Hydroxyglutarate in kidney cancer
Alterations in metabolism are now considered a hallmark of cancer. One of the clearest links between metabolism and malignancy… 
2013
2013
Reply to Struys: Role of biomarker of 2-hydroxyglutarate in acute myeloid leukemia
We agree with E. A. Struys’ point (1) that 2-hydroxyglutarate (2-HG) consists of two distinct forms, l-2-hydroxyglutarate (L2HG… 
2011
2011
Mutational analysis of D2HGDH and L2HGDH in brain tumours without IDH1 or IDH2 mutations
Heterozygous mutations in the highly homologous genes encoding cytosolic isocitrate dehydrogenase 1 (IDH1) and mitochondrial… 
2010
2010
Identification of novel L2HGDH gene mutations and update of the pathological spectrum
L-2-hydroxyglutaric aciduria (L-2-HGA, MIM 236792) is a neurometabolic disorder caused by the toxic accumulation of high… 
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