Ki16425

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2017
051020032017

Papers overview

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2012
2012
An enantionselective synthesis of both enantiomers of Ki16425, which possesses selective LPA antagonistic activity, was achieved… (More)
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2011
2011
Autotaxin (ATX) is a multifunctional ecto-type phosphodiesterase that converts lysophospholipids, such as lysophosphatidylcholine… (More)
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2010
2010
The bioactive phospholipid, lysophosphatidic acid (LPA), acting through at least five distinct receptors LPA1-LPA5, plays… (More)
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Highly Cited
2008
Highly Cited
2008
Lysophosphatidic acid (LPA) is enriched in ascites of ovarian cancer patients and is involved in growth and invasion of ovarian… (More)
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Highly Cited
2007
Highly Cited
2007
Tubulointerstitial fibrosis in chronic renal disease is strongly associated with progressive loss of renal function. We studied… (More)
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Highly Cited
2006
Highly Cited
2006
Autotaxin (ATX) is a cancer-associated motogen that has multiple biological activities in vitro through the production of… (More)
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2006
2006
We report here a novel role for the constitutively active lysophosphatidic acid receptor-1 (LPA(1)) receptor in providing… (More)
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2006
2006
Lysophosphatidic acid (LPA) is a bioactive lipid that has pleiotropic effects on a variety of cell types and enhances the… (More)
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Highly Cited
2004
Highly Cited
2004
Cytokines and growth factors in malignant ascites are thought to modulate a variety of cellular activities of cancer cells and… (More)
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Highly Cited
2003
Highly Cited
2003
Lysophosphatidic acid (LPA) exerts a variety of biological responses through specific receptors: three subtypes of the EDG-family… (More)
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