KcsA protein, Streptomyces coelicolor
National Institutes of Health
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The effect of ion binding in the selectivity filter of the potassium channel KcsA is investigated by combining amide I Fourier…
The prototypical prokaryotic potassium channel KcsA alters its pore depending on the ambient potassium; at high potassium, it…
Ion permeation and selectivity, key features in ion channel function, are believed to arise from a complex ensemble of energetic…
Phospholipid headgroups act as major determinants in proper folding of oligomeric membrane proteins. The K+-channel KcsA is the…
Protein aggregation is a result of malfunction in protein folding, assembly, and transport, caused by protein mutation and/or…
Pulsed electron-electron double-resonance (PELDOR) measurements are presented from the potassium ion channel KcsA both…
Antiamoebin (AAM) is a polypeptide antibiotic that is capable of forming ion channels in phospholipid membranes; planar bilayer…