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KX-01

National Institutes of Health

Papers overview

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2016
2016
Abstract 3859: Peptidomimetic Src kinase inhibitor KX-01 sensitizes estrogen receptor α-negative breast tumor xenografts to tamoxifen by inducing ERα re-expression
Unlike breast cancer that is positive for estrogen receptor α (ERα) or amplified/overexpressed HER2/neu, there are no targeted… 
2014
2014
Abstract 5479: Antitumor effect of KX-01, a novel Src and tubulin inhibitor, in triple negative breast cancer cells
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Background: Src kinases have been involved in cell… 
2014
2014
Antitumor effect of KX-01, a novel Src and tubulin inhibitor, in triple negative breast cancer cells
2012
2012
Preclinical Development Peptidomimetic Src / Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth , Metastasis in Human ER / PR / HER 2-Negative Tumor Xenografts
Src kinase is elevated in breast tumors that are ER/PR negative and do not overexpress HER2, but clinical trials with Src… 
2012
2012
684 SITES AND SURVIVAL OF METASTATIC HEPATOCELLULAR CARCINOMA: ANALYSIS OF A NATIONWIDE INPATIENT DATABASE FROM THE UNITED STATES
2009
2009
Abstract 2535: KX-01, a novel Src kinase inhibitor directed towards the peptide substrate site, induces robust apoptosis and synergizes with tamoxifen and chemotherapy in breast cancer
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC New therapeutic regimens are needed to increase… 
2008
2008
Antitumor effect of KX-01, a novel Src and tubulin inhibitor, in triple negative breast cancer cells
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