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KRN 633

Known as: KRN-633, KRN633 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
The in vitro effect of VEGF receptor inhibition on primary alveolar osteoblast nodule formation.
BACKGROUND Vascular endothelial growth factor (VEGF) is a master regulator and is required for the effective coupling of… 
2018
2018
Establishment of an abnormal vascular patterning model in the mouse retina.
2015
2015
Regression of retinal capillaries following N‐methyl‐D‐aspartate‐induced neurotoxicity in the neonatal rat retina
Degeneration of retinal capillaries occurs following N‐methyl‐D‐aspartate (NMDA)‐induced retinal neurotoxicity, and the degree of… 
2014
2014
Treatment of newborn mice with inhibitors of vascular endothelial growth factor receptor tyrosine kinase induces abnormal retinal vascular patterning.
We have previously reported that treatment of newborn mice with KRN633, a vascular endothelial growth factor (VEGF) receptor… 
2013
2013
KRN633, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, induces intrauterine growth restriction in mice.
We previously reported that treatment with KRN633, a vascular endothelial growth factor receptor tyrosine kinase inhibitor… 
2011
2011
Vascular endothelial growth factor stimulates osteoblastic differentiation of cultured human periosteal-derived cells expressing vascular endothelial growth factor receptors
Angiogenesis plays an important role in bone development and postnatal bone fracture repair. Vascular endothelial growth factor… 
2011
2011
Role of protein kinase C β and vascular endothelial growth factor receptor in malignant pleural mesothelioma: Therapeutic implications and the usefulness of Caenorhabditis elegans model organism
Purpose: To examine the role of both protein kinase C (PKC)-β and vascular endothelial growth factor receptor (VEGFR)-2 in… 
2011
2011
Effects of Lovastatin combined with KRN633 on cholangiocarcinoma cell line QBC939
Objective To investigate the effects of Lovastatin combined with KRN633,a selective inhibitor of vascular endothelial growth… 
2010
2010
Effects of KRN633, an inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase, on vascular development of placenta and fetus of mid-pregnancy in mice.
Inhibition of the vascular endothelial growth factor (VEGF) signaling pathway during pregnancy contributes to several pathologic… 
2006
2006
Improvement by solid dispersion of the bioavailability of KRN633, a selective inhibitor of VEGF receptor-2 tyrosine kinase, and identification of its potential therapeutic window
KRN633 is a potent inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases. However, it is poorly water… 
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