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KREMEN2 gene
Known as:
KRM2
, MGC10791
, kringle containing transmembrane protein 2
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Knockdown of KREMEN2 inhibits tumor proliferation and metastasis in gastric cancer.
Beibei Chen
,
Saiqi Wang
,
+8 authors
Xiaobing Chen
Journal of Clinical Oncology
2020
Corpus ID: 219780242
e16555 Background: KREMEN2 is an important regulator of classical Wnt/β-catenin signaling pathway. However, the relationship…
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2019
2019
Kremen1-induced cell death is regulated by homo- and heterodimerization
I. Sumia
,
A. Pierani
,
F. Causeret
Cell Death Discovery
2019
Corpus ID: 141506660
In multicellular organisms, cell death pathways allow the removal of abnormal or unwanted cells. Their dysregulation can lead…
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2016
2016
Diphtheria Toxin-Induced Cell Death Triggers Wnt-Dependent Hair Cell Regeneration in Neonatal Mice
Lingxiang Hu
,
Jingrong Lu
,
Hao Chiang
,
Hao Wu
,
A. Edge
,
Fuxin Shi
The Journal of Neuroscience
2016
Corpus ID: 3497185
Cochlear hair cells (HCs), the sensory cells that respond to sound, do not regenerate after damage in adult mammals, and their…
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2015
2015
Evidence for several independent genetic variants affecting lipoprotein (a) cholesterol levels.
Wensheng Lu
,
Yuching Cheng
,
+13 authors
Mao Fu
Human molecular genetics
2015
Corpus ID: 18089339
Lipoprotein (a) [Lp(a)] is an independent risk factor for atherosclerosis-related events that is under strong genetic control…
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2014
2014
Osteoblast-Specific Krm2 Overexpression and Lrp5 Deficiency Have Different Effects on Fracture Healing in Mice
A. Liedert
,
Viktoria Röntgen
,
+7 authors
A. Ignatius
PloS one
2014
Corpus ID: 26087394
The canonical Wnt/β-catenin pathway plays a key role in the regulation of bone remodeling in mice and humans. Two transmembrane…
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Highly Cited
2010
Highly Cited
2010
Negative Regulation of Bone Formation by the Transmembrane Wnt Antagonist Kremen-2
J. Schulze
,
S. Seitz
,
+15 authors
T. Schinke
PloS one
2010
Corpus ID: 16078920
Wnt signalling is a key pathway controlling bone formation in mice and humans. One of the regulators of this pathway is Dkk1…
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Highly Cited
2010
Highly Cited
2010
Dkk1 Stabilizes Wnt Co-Receptor LRP6: Implication for Wnt Ligand-Induced LRP6 Down-Regulation
Yonghe Li
,
Wenyan Lu
,
Taj D. King
,
Chia-Chen Liu
,
G. Bijur
,
G. Bu
PloS one
2010
Corpus ID: 3836583
Background The low density lipoprotein receptor-related protein-6 (LRP6) is an essential co-receptor for canonical Wnt signaling…
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Highly Cited
2007
Highly Cited
2007
Kremen is required for neural crest induction in Xenopus and promotes LRP6-mediated Wnt signaling
Christine Hassler
,
C. Cruciat
,
Ya-Lin Huang
,
S. Kuriyama
,
R. Mayor
,
C. Niehrs
Development
2007
Corpus ID: 22694787
Kremen 1 and 2 (Krm1/2) are transmembrane receptors for Wnt antagonists of the Dickkopf (Dkk) family and function by inhibiting…
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2006
2006
The MRH Protein Erlectin Is a Member of the Endoplasmic Reticulum Synexpression Group and Functions in N-Glycan Recognition*
C. Cruciat
,
Christine Hassler
,
C. Niehrs
Journal of Biological Chemistry
2006
Corpus ID: 25108154
Kremen1 and 2 (Krm1/2) are coreceptors for Dickkopf1 (Dkk1), an antagonist of Wnt/β-catenin signaling, and play a role in head…
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Highly Cited
2003
Highly Cited
2003
Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling.
B. Mao
,
C. Niehrs
Gene
2003
Corpus ID: 28222255
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