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KR 62980

Known as: KR-62980, KR62980 
National Institutes of Health

Papers overview

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2015
2015
Antiallergic Function of KR62980, a Peroxisome Proliferator-Activated Receptor-γ Agonist, in a Mouse Allergic Rhinitis Model
Purpose Peroxisome proliferator-activated receptor γ (PPAR-γ) has been shown to play an important role in the control of… 
2014
2014
KR-62980 suppresses lipid metabolism through inhibition of cytosolic NADP isocitrate dehydrogenase in zebrafish.
Peroxisome proliferator-activated receptor γ (PPARγ) is a target of antidiabetic drugs. However, many PPARγ activators, including… 
2014
2014
KR-62980 suppresses lipid metabolism through inhibition of cytosolic NADP isocitrate dehydrogenase in zebrafish.
Abstract Peroxisome proliferator-activated receptor γ (PPARγ) is a target of antidiabetic drugs. However, many PPARγ activators… 
2011
2011
Neuroprotective effects of KR-62980, a new PPARγ agonist, against chemical ischemia–reperfusion in SK-N-SH cells
2011
2011
Dose-independent pharmacokinetics of a new peroxisome proliferator-activated receptor-γ agonist, KR-62980, in Sprague-Dawley rats and ICR mice
The pharmacokinetics of a novel peroxisome proliferator-activated receptor-γ agonist, KR-62980, were characterized in vitro with… 
2010
2010
Anti-allergic function and regulatory mechanisms of KR62980 in allergen-induced airway inflammation.
2009
2009
Augmentation of PPARgamma-TAZ interaction contributes to the anti-adipogenic activity of KR62980.
2008
2008
In vitro metabolism of a novel PPAR gamma agonist, KR-62980, and its stereoisomer, KR-63198, in human liver microsomes and by recombinant cytochrome P450s.
1. KR-62980 and its stereoisomer KR-63198 are novel and selective peroxisome proliferator-activated receptor gamma (PPAR gamma… 
Highly Cited
2007
Highly Cited
2007
Apoptotic Action of Peroxisome Proliferator-Activated Receptor-γ Activation in Human Non–Small-Cell Lung Cancer Is Mediated via Proline Oxidase-Induced Reactive Oxygen Species Formation
Peroxisome proliferator-activated receptor (PPAR)-γ ligands have been shown to inhibit human lung cancers by inducing apoptosis… 
Highly Cited
2006
Highly Cited
2006
Differential anti-proliferative actions of peroxisome proliferator-activated receptor-gamma agonists in MCF-7 breast cancer cells.
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