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KP-496

National Institutes of Health

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BenzoatesThiazoles

Papers overview

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2010
2010
Effect of inhaled KP-496, a novel dual antagonist of the cysteinyl leukotriene and thromboxane A2 receptors, on a bleomycin-induced pulmonary fibrosis model in mice.
2009
2009
Effects of KP-496, a novel dual antagonist for cysteinyl leukotriene receptor 1 and thromboxane A2 receptor, on Sephadex-induced airway inflammation in rats.
Bronchial asthma is characterized by chronic airway inflammation. Eosinophils are involved in airway inflammation and play… 
2009
2009
The Effects of Inhaled KP-496, a Novel Dual Antagonist for Cysteinyl Leukotriene Receptor and Thromboxane A2 Receptor, on Allergic Asthmatic Responses in Guinea Pigs
Aims: The aim of this study was to evaluate the effects of inhaled KP-496, a novel dual antagonist for cysteinyl leukotriene… 
2008
2008
Effects of KP‐496, a novel dual antagonist at the cysteinyl leukotriene receptor 1 and the thromboxane A2 receptor, on airway obstruction in guinea pigs
KP‐496 is a novel dual antagonist for cysteinyl leukotriene receptor 1 (CysLT1) and thromboxane A2 (TXA2) receptor (TP). The aim… 
2008
2008
Effects of KP-496, a novel dual antagonist of leukotriene D4 and thromboxane A2 receptors on nasal blockage in guinea pig models of allergic rhinitis
Abstract.Objective and design:KP-496 is a novel dual antagonist for leukotriene (LT) D4 and thromboxane (TX) A2 receptors. We… 
2008
2008
Effects of Inhaled KP-496, a Novel Dual Antagonist for Cysteinyl Leukotrienes Receptor and Thromboxane A2 Receptor, on Allergic Asthmatic Responses in Guinea Pigs
2007
2007
Effects of KP-496, a Novel Dual Antagonist for Cysteinyl Leukotriene Receptor (CysLT1R) and Thromboxane A2 Receptor (TP), on Porcine Pancreas Elastase Induced Emphysema in Mice
2006
2006
Pharmacological Profile of KP-496, a Novel Dual Antagonist for Cysteinyl Leukotriene Receptor (CysLT1R) and Thromboxane A2 Receptor (TP)
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