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KLHDC8B gene

Known as: kelch domain containing 8B, KLHDC8B, MGC35097 
National Institutes of Health

Papers overview

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2018
2018
Combined linkage and association analysis of classical Hodgkin lymphoma
The heritability of classical Hodgkin lymphoma (cHL) has yet to be fully deciphered. We report a family with five members… 
2012
2012
The Kelch Protein KLHDC8B Guards against Mitotic Errors, Centrosomal Amplification, and Chromosomal Instability
Background: The large multinucleated Reed-Sternberg cell is the driving force behind Hodgkin lymphoma pathogenesis. Results… 
2011
2011
Analysis of KLHDC8B in familial nodular lymphocyte predominant Hodgkin lymphoma
working group report. Biology of Blood and Marrow Transplantation, 11, 945–956. Flowers, M.E., Apperley, J.F., van Besien, K… 
Review
2010
Review
2010
KLHDC8B in Hodgkin lymphoma and possibly twinning
A key feature of Hodgkin lymphoma is that the malignant cells are binucleated, as a consequence of failed cytokinesis. We… 
2010
2010
Mutations in a gene encoding a midbody protein in binucleated Reed-Sternberg cells of Hodgkin lymphoma
Classical Hodgkin lymphoma (cHL) is a cancer in which malignant "Reed-Sternberg" cells comprise just a fraction of the bulk of… 
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