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KIT gene

Known as: KIT proto-oncogene receptor tyrosine kinase, PBT, STEM CELL FACTOR RECEPTOR 
Cloned cancer gene for Familial gastrointestinal stromal tumors (GIST), KIT proto-oncogene encodes a putative transmembrane receptor tyrosine kinase… 
National Institutes of Health

Related topics

Related topics

13 relations
4q11-q12C-KIT GeneGastrointestinal Stromal TumorsGerm cell tumor

Papers overview

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Highly Cited
2007
Highly Cited
2007
Superheating in linear polymers studied by ultrafast nanocalorimetry
Abstract.To study phase transition kinetics on submillisecond time scale a sensitive ultrafast nanocalorimeter was constructed… 
Highly Cited
1996
Highly Cited
1996
Constitutive activation of c-kit in FMA3 murine mastocytoma cells caused by deletion of seven amino acids at the juxtamembrane domain.
A peculiar point mutation results in constitutive activation of c-kit receptor tyrosine kinase (KIT) in three different tumor… 
Highly Cited
1995
Highly Cited
1995
Identification and characterization of a soluble c-kit receptor produced by human hematopoietic cell lines.
Stem cell factor (SCF) triggers cell growth by binding to cell surface c-kit receptors. Soluble forms of several cytokine… 
Highly Cited
1994
Highly Cited
1994
Effects of interleukin-3 and c-kit ligand on the survival of various classes of human hematopoietic progenitor cells.
We examined the effects of interleukin-3 (IL-3) and c-kit ligand (KL) on the survival of differentiated hematopoietic progenitor… 
Highly Cited
1994
Highly Cited
1994
AML: immunophenotypic heterogeneity and prognostic significance of c-kit expression.
Antigenic profiles in AML that have generally accepted prognostic significance, and allow treatment stratification, have not yet… 
Highly Cited
1994
Highly Cited
1994
Expression of the c-kit receptor in human lymphomas is restricted to Hodgkin's disease and CD30+ anaplastic large cell lymphomas.
The product of the proto-oncogene c-kit is a transmembrane receptor protein that plays an important role in the regulation of… 
Highly Cited
1992
Highly Cited
1992
Isolation and characterization of a monoclonal antibody that recognizes the human c-kit receptor.
Stem cell factor (SCF) stimulates the growth of burst-forming unit-erythroid (BFU-E) and colony-forming unit granulocyte… 
Highly Cited
1991
Highly Cited
1991
IL-4 regulates c-kit proto-oncogene product expression in human mast and myeloid progenitor cells.
The c-kit proto-oncogene encodes the receptor for a novel hemopoietic cytokine, termed stem cell factor (SCF) or mast cell growth… 
Highly Cited
1990
Highly Cited
1990
Isolation and characterization of the alpha platelet-derived growth factor receptor from rat olfactory epithelium
We have cloned and characterized a new member of the receptor tyrosine kinase family. The cDNA clone, isolated from a rat… 
Highly Cited
1988
Highly Cited
1988
c-kit protein, a transmembrane kinase: identification in tissues and characterization
The proto-oncogene c-kit encodes a transmembrane kinase which is related to the receptors for colony-stimulating factor type 1… 
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