KIT gene

Known as: KIT proto-oncogene receptor tyrosine kinase, PBT, STEM CELL FACTOR RECEPTOR 
Cloned cancer gene for Familial gastrointestinal stromal tumors (GIST), KIT proto-oncogene encodes a putative transmembrane receptor tyrosine kinase… (More)
National Institutes of Health

Papers overview

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Highly Cited
1998
Highly Cited
1998
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the human digestive tract, but their molecular… (More)
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Highly Cited
1994
Highly Cited
1994
1. Interstitial cells of Cajal (ICs) have been proposed as pacemakers in the gastrointestinal tract. We studied the… (More)
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Highly Cited
1992
Highly Cited
1992
A discovery that the protooncogene encoding the receptor tyrosine kinase, c-kit, is allelic with the Dominant white spotting (W… (More)
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Highly Cited
1991
Highly Cited
1991
The ligand (KL) for the c-kit receptor is a growth factor encoded at the mouse steel (Sl) locus. KL exists in both cell surface… (More)
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Highly Cited
1991
Highly Cited
1991
Recent studies have shown that the dominant white spotting (W) locus encodes the proto-oncogene c-kit, a member of the tyrosine… (More)
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Highly Cited
1990
Highly Cited
1990
Mutations at the steel locus (Sl) of the mouse affect the same cellular targets as mutations at the white spotting locus (W… (More)
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Highly Cited
1990
Highly Cited
1990
We have cloned a partial cDNA encoding murine stem cell factor (SCF) and show that the gene is syntenic with the Sl locus on… (More)
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Highly Cited
1988
Highly Cited
1988
Mutations at the W locus in the mouse have pleiotropic effects on embryonic development and hematopoiesis. The characteristic… (More)
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Highly Cited
1988
Highly Cited
1988
Mice carrying mutations at the W locus located on chromosome 5 are characterized by severe macrocytic anaemia, lack of hair… (More)
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Highly Cited
1987
Highly Cited
1987
Structural features of v-kit, the oncogene of HZ4 feline sarcoma virus, suggested that this gene arose by transduction and… (More)
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