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KIT NP_000213.1:p.D816V

Known as: CD117 Antigen D816V, Stem Cell Factor Receptor D816V, KIT NP_000213.1:p.Asp816Val 
A change in the amino acid residue at position 816 in the mast/stem cell growth factor receptor Kit protein where asparagine has been replaced by… 
National Institutes of Health

Related topics

Related topics

2 relations
KIT Gene MutationKIT NM_000222.2:c.2447A>T

Papers overview

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Highly Cited
2016
Highly Cited
2016
Clinical, immunophenotypic, and molecular characteristics of well-differentiated systemic mastocytosis.
2015
2015
Nilotinib in patients with systemic mastocytosis: analysis of the phase 2, open-label, single-arm nilotinib registration study
PurposeActivating KIT mutations are part of the pathogenesis of systemic mastocytosis (SM). Nilotinib is a tyrosine kinase… 
Highly Cited
2014
Highly Cited
2014
Proposed diagnostic algorithm for patients with suspected mastocytosis: a proposal of the European Competence Network on Mastocytosis
Mastocytosis is an emerging differential diagnosis in patients with more or less specific mediator‐related symptoms. In some of… 
Highly Cited
2014
Highly Cited
2014
Sensitive KIT D816V mutation analysis of blood as a diagnostic test in mastocytosis
The recent progress in sensitive KIT D816V mutation analysis suggests that mutation analysis of peripheral blood (PB) represents… 
Highly Cited
2014
Highly Cited
2014
A new human mast cell line expressing a functional IgE receptor converts to tumorigenic growth by KIT D816V transfection.
In systemic mastocytosis (SM), clinical problems arise from factor-independent proliferation of mast cells (MCs) and the… 
Highly Cited
2014
Highly Cited
2014
The KIT D816V allele burden predicts survival in patients with mastocytosis and correlates with the WHO type of the disease
KIT D816V is present in a majority of patients with systemic mastocytosis (SM). We determined the KIT D816V allele burden by… 
Highly Cited
2013
Highly Cited
2013
The KIT D816V expressed allele burden for diagnosis and disease monitoring of systemic mastocytosis
The activating KIT D816V mutation plays a central role in the pathogenesis, diagnosis, and targeted treatment of systemic… 
2013
2013
KIT D816V mutation burden does not correlate to clinical manifestations of indolent systemic mastocytosis.
Highly Cited
2010
Highly Cited
2010
High frequency of concomitant mastocytosis in patients with acute myeloid leukemia exhibiting the transforming KIT mutation D816V
Highly Cited
2008
Highly Cited
2008
Unique Effects of KIT D816V in BaF3 Cells: Induction of Cluster Formation, Histamine Synthesis, and Early Mast Cell Differentiation Antigens1
Oncogenic tyrosine kinases (TK) usually convert growth factor-dependent cells to factor independence with autonomous… 
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